VPS38/UVRAG and ATG14, the variant regulatory subunits of the ATG6/Beclin1-PI3K complexes, are crucial for the biogenesis of the yolk organelles and are transcriptionally regulated in the oocytes of the vector Rhodnius prolixus.
In insects the reserve proteins are stored in the oocytes into endocytic-originated vesicles named yolk organelles. VPS38/UVRAG and ATG14 are the variant regulatory subunits of two class-III ATG6/Beclin1 PI3K complexes that regulate the recruitment of the endocytic (complex II) and autophagic (compl...
Guardado en:
Autores principales: | Priscila H Vieira, Claudia F Benjamim, Georgia Atella, Isabela Ramos |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/77d55d16af0741a2868874c6bc4f7131 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Oxidation of Atg3 and Atg7 mediates inhibition of autophagy
por: Karen Frudd, et al.
Publicado: (2018) -
ATG 4B Serves a Crucial Role in RCE-4-Induced Inhibition of the Bcl-2–Beclin 1 Complex in Cervical Cancer Ca Ski Cells
por: Fang-Fang You, et al.
Publicado: (2021) -
A semisynthetic Atg3 reveals that acetylation promotes Atg3 membrane binding and Atg8 lipidation
por: Yi-Tong Li, et al.
Publicado: (2017) -
Atg4 proteolytic activity can be inhibited by Atg1 phosphorylation
por: Jana Sánchez-Wandelmer, et al.
Publicado: (2017) -
Autophagy-Related Protein ATG18 Regulates Apicoplast Biogenesis in Apicomplexan Parasites
por: Priyanka Bansal, et al.
Publicado: (2017)