Elevated levels of Wnt signaling disrupt thymus morphogenesis and function
Abstract All vertebrates possess a thymus, whose epithelial microenvironment is essential for T cell development and maturation. Despite the importance of the thymus for cellular immune defense, many questions surrounding its morphogenesis remain unanswered. Here, we demonstrate that, in contrast to...
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Main Authors: | Jeremy B. Swann, Christiane Happe, Thomas Boehm |
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Format: | article |
Language: | EN |
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Nature Portfolio
2017
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Online Access: | https://doaj.org/article/77d9ffad1f2241eab4bd1f1a5200e4ce |
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