Effects of replacing wheat flour with detoxified ginkgo nut powder on lipid metabolism of obese C57BL/6J male mice

Effects of detoxified ginkgo nut powder (DGP) on lipid metabolism of obese mice were evaluated. Mice were divided into four groups: normal group (NC), hyperlipidaemic group (HC, high-fat feed), HC/DGP group (high-fat diet + DGP), and HC/flour group (HC/WF, high-fat diet + flour). After 18 weeks, liv...

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Autores principales:	Haiying Liu, Xinli Pei, Kaiwen Shi, Jing Wang, Fei Han, Aike Li
Formato:	article
Lenguaje:	EN
Publicado:	Taylor & Francis Group 2018
Materias:	detoxified ginkgo nut powder obesity body adiposity high-fat diet mice Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/77de5cc8eef44d1bb879a77b917839cd
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spelling	oai:doaj.org-article:77de5cc8eef44d1bb879a77b917839cd2021-11-26T11:19:46ZEffects of replacing wheat flour with detoxified ginkgo nut powder on lipid metabolism of obese C57BL/6J male mice0954-01051465-344310.1080/09540105.2017.1358255https://doaj.org/article/77de5cc8eef44d1bb879a77b917839cd2018-01-01T00:00:00Zhttp://dx.doi.org/10.1080/09540105.2017.1358255https://doaj.org/toc/0954-0105https://doaj.org/toc/1465-3443Effects of detoxified ginkgo nut powder (DGP) on lipid metabolism of obese mice were evaluated. Mice were divided into four groups: normal group (NC), hyperlipidaemic group (HC, high-fat feed), HC/DGP group (high-fat diet + DGP), and HC/flour group (HC/WF, high-fat diet + flour). After 18 weeks, liver and body fat weights of HC/DGP were significantly lower than those of HC and HC/WF, but similar to those of NC. The serum and hepatic levels of serum triglyceride, total cholesterol, low-density lipoprotein cholesterol, leptin and resistin in HC/DGP were similar to those in NC but significantly lower than those in HC and HC/WF. In addition, the expression levels of PPARα (peroxisome proliferator-activated receptor alpha) in liver and of hormone-sensitive lipase, adipose triglyceride lipase, and monoacylglycerol lipase in epididymal fat were higher in HC/DGP than in other groups. The results revealed that DGP may reduce inflammation and promote normal lipid metabolism.Haiying LiuXinli PeiKaiwen ShiJing WangFei HanAike LiTaylor & Francis Grouparticledetoxified ginkgo nut powderobesitybody adiposityhigh-fat dietmiceAgriculture (General)S1-972Immunologic diseases. AllergyRC581-607ENFood and Agricultural Immunology, Vol 29, Iss 1, Pp 39-55 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	detoxified ginkgo nut powder obesity body adiposity high-fat diet mice Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607
spellingShingle	detoxified ginkgo nut powder obesity body adiposity high-fat diet mice Agriculture (General) S1-972 Immunologic diseases. Allergy RC581-607 Haiying Liu Xinli Pei Kaiwen Shi Jing Wang Fei Han Aike Li Effects of replacing wheat flour with detoxified ginkgo nut powder on lipid metabolism of obese C57BL/6J male mice
description	Effects of detoxified ginkgo nut powder (DGP) on lipid metabolism of obese mice were evaluated. Mice were divided into four groups: normal group (NC), hyperlipidaemic group (HC, high-fat feed), HC/DGP group (high-fat diet + DGP), and HC/flour group (HC/WF, high-fat diet + flour). After 18 weeks, liver and body fat weights of HC/DGP were significantly lower than those of HC and HC/WF, but similar to those of NC. The serum and hepatic levels of serum triglyceride, total cholesterol, low-density lipoprotein cholesterol, leptin and resistin in HC/DGP were similar to those in NC but significantly lower than those in HC and HC/WF. In addition, the expression levels of PPARα (peroxisome proliferator-activated receptor alpha) in liver and of hormone-sensitive lipase, adipose triglyceride lipase, and monoacylglycerol lipase in epididymal fat were higher in HC/DGP than in other groups. The results revealed that DGP may reduce inflammation and promote normal lipid metabolism.
format	article
author	Haiying Liu Xinli Pei Kaiwen Shi Jing Wang Fei Han Aike Li
author_facet	Haiying Liu Xinli Pei Kaiwen Shi Jing Wang Fei Han Aike Li
author_sort	Haiying Liu
title	Effects of replacing wheat flour with detoxified ginkgo nut powder on lipid metabolism of obese C57BL/6J male mice
title_short	Effects of replacing wheat flour with detoxified ginkgo nut powder on lipid metabolism of obese C57BL/6J male mice
title_full	Effects of replacing wheat flour with detoxified ginkgo nut powder on lipid metabolism of obese C57BL/6J male mice
title_fullStr	Effects of replacing wheat flour with detoxified ginkgo nut powder on lipid metabolism of obese C57BL/6J male mice
title_full_unstemmed	Effects of replacing wheat flour with detoxified ginkgo nut powder on lipid metabolism of obese C57BL/6J male mice
title_sort	effects of replacing wheat flour with detoxified ginkgo nut powder on lipid metabolism of obese c57bl/6j male mice
publisher	Taylor & Francis Group
publishDate	2018
url	https://doaj.org/article/77de5cc8eef44d1bb879a77b917839cd
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Effects of replacing wheat flour with detoxified ginkgo nut powder on lipid metabolism of obese C57BL/6J male mice

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