Highly active antiretroviral therapies are effective against HIV-1 cell-to-cell transmission.

HIV-1 cell-to-cell transmission allows for 2-3 orders of magnitude more efficient viral spread than cell-free dissemination. The high local multiplicity of infection (MOI) observed at cell-cell contact sites may lower the efficacy of antiretroviral therapies (ART). Here we test the efficacy of commo...

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Bibliographic Details
Main Authors: Luis M Agosto, Peng Zhong, James Munro, Walther Mothes
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2014
Subjects:
Online Access:https://doaj.org/article/77e62d58c4a947549b61ec6e58e2b001
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