Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases.
Holliday junctions (HJs) are cruciform DNA structures that are created during recombination events. It is a matter of considerable importance to determine the resolvase(s) that promote resolution of these structures. We previously reported that C. elegans GEN-1 is a symmetrically cleaving HJ resolvi...
Guardado en:
Autores principales: | Ana Agostinho, Bettina Meier, Remi Sonneville, Marlène Jagut, Alexander Woglar, Julian Blow, Verena Jantsch, Anton Gartner |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2013
|
Materias: | |
Acceso en línea: | https://doaj.org/article/77f48a1516834de1a62d2051469a8622 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Slx5-Slx8 ubiquitin ligase targets active pools of the Yen1 nuclease to limit crossover formation
por: Ibtissam Talhaoui, et al.
Publicado: (2018) -
Exploring the Structures and Functions of Macromolecular SLX4-Nuclease Complexes in Genome Stability
por: Brandon J. Payliss, et al.
Publicado: (2021) -
Abraxas suppresses DNA end resection and limits break-induced replication by controlling SLX4/MUS81 chromatin loading in response to TOP1 inhibitor-induced DNA damage
por: Xiao Wu, et al.
Publicado: (2021) -
Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma
por: T. P. MacGregor, et al.
Publicado: (2018) -
Sequencing analysis of SLX4/FANCP gene in Italian familial breast cancer cases.
por: Irene Catucci, et al.
Publicado: (2012)