Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension

Background and Aims: An important factor in the development of vascular wall lesions is the degradation of the elastic fiber major protein – elastin. Elastin peptides (EDP) derived from this degradation are present in the circulation and are a stimulus for the production of anti-elastin antibodies (...

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Autores principales: Nikolov A., Blazhev A., Tzekova M., Kostov K., Popovski N.
Formato: article
Lenguaje:EN
Publicado: Sciendo 2019
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Acceso en línea:https://doaj.org/article/77f6311d454a41eea5a9424df62962ce
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spelling oai:doaj.org-article:77f6311d454a41eea5a9424df62962ce2021-12-02T14:59:50ZLipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension0324-175010.2478/amb-2019-0004https://doaj.org/article/77f6311d454a41eea5a9424df62962ce2019-02-01T00:00:00Zhttps://doi.org/10.2478/amb-2019-0004https://doaj.org/toc/0324-1750Background and Aims: An important factor in the development of vascular wall lesions is the degradation of the elastic fiber major protein – elastin. Elastin peptides (EDP) derived from this degradation are present in the circulation and are a stimulus for the production of anti-elastin antibodies (AEAbs) IgM, IgG and IgA. The aim of this study was to investigate the possible association between AEAbs, lipid indices and the development of microvascular complications.Nikolov A.Blazhev A.Tzekova M.Kostov K.Popovski N.Sciendoarticlediabetes mellitusarterial hypertensionanti-elastin antibodies (igg, igm, iga)microangiopathylipid indicesMedicineRENActa Medica Bulgarica, Vol 46, Iss 1, Pp 21-27 (2019)
institution DOAJ
collection DOAJ
language EN
topic diabetes mellitus
arterial hypertension
anti-elastin antibodies (igg, igm, iga)
microangiopathy
lipid indices
Medicine
R
spellingShingle diabetes mellitus
arterial hypertension
anti-elastin antibodies (igg, igm, iga)
microangiopathy
lipid indices
Medicine
R
Nikolov A.
Blazhev A.
Tzekova M.
Kostov K.
Popovski N.
Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension
description Background and Aims: An important factor in the development of vascular wall lesions is the degradation of the elastic fiber major protein – elastin. Elastin peptides (EDP) derived from this degradation are present in the circulation and are a stimulus for the production of anti-elastin antibodies (AEAbs) IgM, IgG and IgA. The aim of this study was to investigate the possible association between AEAbs, lipid indices and the development of microvascular complications.
format article
author Nikolov A.
Blazhev A.
Tzekova M.
Kostov K.
Popovski N.
author_facet Nikolov A.
Blazhev A.
Tzekova M.
Kostov K.
Popovski N.
author_sort Nikolov A.
title Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension
title_short Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension
title_full Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension
title_fullStr Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension
title_full_unstemmed Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension
title_sort lipid indices, elastin turnover and the development of microvascular complications – a study in diabetic patients with arterial hypertension
publisher Sciendo
publishDate 2019
url https://doaj.org/article/77f6311d454a41eea5a9424df62962ce
work_keys_str_mv AT nikolova lipidindiceselastinturnoverandthedevelopmentofmicrovascularcomplicationsastudyindiabeticpatientswitharterialhypertension
AT blazheva lipidindiceselastinturnoverandthedevelopmentofmicrovascularcomplicationsastudyindiabeticpatientswitharterialhypertension
AT tzekovam lipidindiceselastinturnoverandthedevelopmentofmicrovascularcomplicationsastudyindiabeticpatientswitharterialhypertension
AT kostovk lipidindiceselastinturnoverandthedevelopmentofmicrovascularcomplicationsastudyindiabeticpatientswitharterialhypertension
AT popovskin lipidindiceselastinturnoverandthedevelopmentofmicrovascularcomplicationsastudyindiabeticpatientswitharterialhypertension
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