Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension
Background and Aims: An important factor in the development of vascular wall lesions is the degradation of the elastic fiber major protein – elastin. Elastin peptides (EDP) derived from this degradation are present in the circulation and are a stimulus for the production of anti-elastin antibodies (...
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oai:doaj.org-article:77f6311d454a41eea5a9424df62962ce2021-12-02T14:59:50ZLipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension0324-175010.2478/amb-2019-0004https://doaj.org/article/77f6311d454a41eea5a9424df62962ce2019-02-01T00:00:00Zhttps://doi.org/10.2478/amb-2019-0004https://doaj.org/toc/0324-1750Background and Aims: An important factor in the development of vascular wall lesions is the degradation of the elastic fiber major protein – elastin. Elastin peptides (EDP) derived from this degradation are present in the circulation and are a stimulus for the production of anti-elastin antibodies (AEAbs) IgM, IgG and IgA. The aim of this study was to investigate the possible association between AEAbs, lipid indices and the development of microvascular complications.Nikolov A.Blazhev A.Tzekova M.Kostov K.Popovski N.Sciendoarticlediabetes mellitusarterial hypertensionanti-elastin antibodies (igg, igm, iga)microangiopathylipid indicesMedicineRENActa Medica Bulgarica, Vol 46, Iss 1, Pp 21-27 (2019) |
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diabetes mellitus arterial hypertension anti-elastin antibodies (igg, igm, iga) microangiopathy lipid indices Medicine R |
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diabetes mellitus arterial hypertension anti-elastin antibodies (igg, igm, iga) microangiopathy lipid indices Medicine R Nikolov A. Blazhev A. Tzekova M. Kostov K. Popovski N. Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension |
description |
Background and Aims: An important factor in the development of vascular wall lesions is the degradation of the elastic fiber major protein – elastin. Elastin peptides (EDP) derived from this degradation are present in the circulation and are a stimulus for the production of anti-elastin antibodies (AEAbs) IgM, IgG and IgA. The aim of this study was to investigate the possible association between AEAbs, lipid indices and the development of microvascular complications. |
format |
article |
author |
Nikolov A. Blazhev A. Tzekova M. Kostov K. Popovski N. |
author_facet |
Nikolov A. Blazhev A. Tzekova M. Kostov K. Popovski N. |
author_sort |
Nikolov A. |
title |
Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension |
title_short |
Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension |
title_full |
Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension |
title_fullStr |
Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension |
title_full_unstemmed |
Lipid Indices, Elastin Turnover and the Development of Microvascular Complications – A Study in Diabetic Patients with Arterial Hypertension |
title_sort |
lipid indices, elastin turnover and the development of microvascular complications – a study in diabetic patients with arterial hypertension |
publisher |
Sciendo |
publishDate |
2019 |
url |
https://doaj.org/article/77f6311d454a41eea5a9424df62962ce |
work_keys_str_mv |
AT nikolova lipidindiceselastinturnoverandthedevelopmentofmicrovascularcomplicationsastudyindiabeticpatientswitharterialhypertension AT blazheva lipidindiceselastinturnoverandthedevelopmentofmicrovascularcomplicationsastudyindiabeticpatientswitharterialhypertension AT tzekovam lipidindiceselastinturnoverandthedevelopmentofmicrovascularcomplicationsastudyindiabeticpatientswitharterialhypertension AT kostovk lipidindiceselastinturnoverandthedevelopmentofmicrovascularcomplicationsastudyindiabeticpatientswitharterialhypertension AT popovskin lipidindiceselastinturnoverandthedevelopmentofmicrovascularcomplicationsastudyindiabeticpatientswitharterialhypertension |
_version_ |
1718389209420529664 |