Cytomegalovirus immediate-early 1 proteins form a structurally distinct protein class with adaptations determining cross-species barriers.

Restriction factors are potent antiviral proteins that constitute a first line of intracellular defense by blocking viral replication and spread. During co-evolution, however, viruses have developed antagonistic proteins to modulate or degrade the restriction factors of their host. To ensure the suc...

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Bibliographic Details
Main Authors: Johannes Schweininger, Myriam Scherer, Franziska Rothemund, Eva-Maria Schilling, Sonja Wörz, Thomas Stamminger, Yves A Muller
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2021
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Online Access:https://doaj.org/article/77fb03220dbd48e8b450e0768989907b
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