GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment

Polypeptide N-acetyl-galactosaminyltransferases (GALNTs) are associated with cancer, but their function in organ-specific metastasis is unclear. Here the authors show that GALNT14 promotes breast cancer metastasis to the lung by enhancing the initiation of metastatic colonies and subsequent growth.

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Autores principales:	Ki-Hoon Song, Mi So Park, Tulip S. Nandu, Shrikanth Gadad, Sang-Cheol Kim, Mi-Young Kim
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/77fddd8454574a1a8462112cfbaa4667
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spelling	oai:doaj.org-article:77fddd8454574a1a8462112cfbaa46672021-12-02T17:31:35ZGALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment10.1038/ncomms137962041-1723https://doaj.org/article/77fddd8454574a1a8462112cfbaa46672016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13796https://doaj.org/toc/2041-1723Polypeptide N-acetyl-galactosaminyltransferases (GALNTs) are associated with cancer, but their function in organ-specific metastasis is unclear. Here the authors show that GALNT14 promotes breast cancer metastasis to the lung by enhancing the initiation of metastatic colonies and subsequent growth.Ki-Hoon SongMi So ParkTulip S. NanduShrikanth GadadSang-Cheol KimMi-Young KimNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ki-Hoon Song Mi So Park Tulip S. Nandu Shrikanth Gadad Sang-Cheol Kim Mi-Young Kim GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment
description	Polypeptide N-acetyl-galactosaminyltransferases (GALNTs) are associated with cancer, but their function in organ-specific metastasis is unclear. Here the authors show that GALNT14 promotes breast cancer metastasis to the lung by enhancing the initiation of metastatic colonies and subsequent growth.
format	article
author	Ki-Hoon Song Mi So Park Tulip S. Nandu Shrikanth Gadad Sang-Cheol Kim Mi-Young Kim
author_facet	Ki-Hoon Song Mi So Park Tulip S. Nandu Shrikanth Gadad Sang-Cheol Kim Mi-Young Kim
author_sort	Ki-Hoon Song
title	GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment
title_short	GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment
title_full	GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment
title_fullStr	GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment
title_full_unstemmed	GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment
title_sort	galnt14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/77fddd8454574a1a8462112cfbaa4667
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GALNT14 promotes lung-specific breast cancer metastasis by modulating self-renewal and interaction with the lung microenvironment

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