Interpretation and significance of the definition of anti-Mullerian hormone in the practice of juvenile gynaecologist

The article presents an overview of the physiological role of anti-Mullerian hormone (AMH) during persons lifetime, the fluctuations of its values from birth to the reproductive period in women, the significance of its determination in the diagnosis and prognosis of treatment outcomes for many gynec...

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Autores principales:	Zaira K. Kumykova, Elena V. Uvarova, Zalina K. Batyrova
Formato:	article
Lenguaje:	RU
Publicado:	IP Berlin A.V. 2021
Materias:	anti-mullerian hormone ovarian reserve adolescent girl Gynecology and obstetrics RG1-991
Acceso en línea:	https://doaj.org/article/780055c550a94010b688bacf38baff6c
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spelling	oai:doaj.org-article:780055c550a94010b688bacf38baff6c2021-12-02T19:22:24ZInterpretation and significance of the definition of anti-Mullerian hormone in the practice of juvenile gynaecologist2079-56962079-583110.26442/20795696.2021.3.200779https://doaj.org/article/780055c550a94010b688bacf38baff6c2021-08-01T00:00:00Zhttps://gynecology.orscience.ru/2079-5831/article/viewFile/76096/56691https://doaj.org/toc/2079-5696https://doaj.org/toc/2079-5831The article presents an overview of the physiological role of anti-Mullerian hormone (AMH) during persons lifetime, the fluctuations of its values from birth to the reproductive period in women, the significance of its determination in the diagnosis and prognosis of treatment outcomes for many gynecological diseases. AMH is produced mainly by preantral and early antral follicles and decreases during the final maturation and luteinization. AMH plays a potential role in preserving the ovarian reserve by performing dual actions. AMH inhibits the initial recruitment of follicles, preventing the influence of stimulating growth factors for recruitment (KIT-ligand, the main fibroblast growth factor). From the moment of puberty, AMH reduces the sensitivity of primary follicles to the follicle-stimulating hormone, reducing the likelihood of their cyclic recruitment. The systematic review data presented the characteristics of the ovarian reserve in a healthy female population aged 0 to 19 years. At birth, very low AMH values were noted with an increase in its level in the first 3 months of life, followed by a monthly increase of 31%. A significant increase in AMH secretion was revealed by the beginning of puberty, then most authors noted a constant level of serum AMH in the adolescent period. The level of AMH in the blood serum decreases with an increase in chronological age by 68% annually and varies during the menstrual cycle. AMH is an important diagnostic tool in pediatric practice when differentiating various causes of puberty disorders, virilization and menstrual cycle disorders in girls.Zaira K. KumykovaElena V. UvarovaZalina K. BatyrovaIP Berlin A.V. articleanti-mullerian hormoneovarian reserveadolescent girlGynecology and obstetricsRG1-991RUГинекология, Vol 23, Iss 3, Pp 230-235 (2021)
institution	DOAJ
collection	DOAJ
language	RU
topic	anti-mullerian hormone ovarian reserve adolescent girl Gynecology and obstetrics RG1-991
spellingShingle	anti-mullerian hormone ovarian reserve adolescent girl Gynecology and obstetrics RG1-991 Zaira K. Kumykova Elena V. Uvarova Zalina K. Batyrova Interpretation and significance of the definition of anti-Mullerian hormone in the practice of juvenile gynaecologist
description	The article presents an overview of the physiological role of anti-Mullerian hormone (AMH) during persons lifetime, the fluctuations of its values from birth to the reproductive period in women, the significance of its determination in the diagnosis and prognosis of treatment outcomes for many gynecological diseases. AMH is produced mainly by preantral and early antral follicles and decreases during the final maturation and luteinization. AMH plays a potential role in preserving the ovarian reserve by performing dual actions. AMH inhibits the initial recruitment of follicles, preventing the influence of stimulating growth factors for recruitment (KIT-ligand, the main fibroblast growth factor). From the moment of puberty, AMH reduces the sensitivity of primary follicles to the follicle-stimulating hormone, reducing the likelihood of their cyclic recruitment. The systematic review data presented the characteristics of the ovarian reserve in a healthy female population aged 0 to 19 years. At birth, very low AMH values were noted with an increase in its level in the first 3 months of life, followed by a monthly increase of 31%. A significant increase in AMH secretion was revealed by the beginning of puberty, then most authors noted a constant level of serum AMH in the adolescent period. The level of AMH in the blood serum decreases with an increase in chronological age by 68% annually and varies during the menstrual cycle. AMH is an important diagnostic tool in pediatric practice when differentiating various causes of puberty disorders, virilization and menstrual cycle disorders in girls.
format	article
author	Zaira K. Kumykova Elena V. Uvarova Zalina K. Batyrova
author_facet	Zaira K. Kumykova Elena V. Uvarova Zalina K. Batyrova
author_sort	Zaira K. Kumykova
title	Interpretation and significance of the definition of anti-Mullerian hormone in the practice of juvenile gynaecologist
title_short	Interpretation and significance of the definition of anti-Mullerian hormone in the practice of juvenile gynaecologist
title_full	Interpretation and significance of the definition of anti-Mullerian hormone in the practice of juvenile gynaecologist
title_fullStr	Interpretation and significance of the definition of anti-Mullerian hormone in the practice of juvenile gynaecologist
title_full_unstemmed	Interpretation and significance of the definition of anti-Mullerian hormone in the practice of juvenile gynaecologist
title_sort	interpretation and significance of the definition of anti-mullerian hormone in the practice of juvenile gynaecologist
publisher	IP Berlin A.V.
publishDate	2021
url	https://doaj.org/article/780055c550a94010b688bacf38baff6c
work_keys_str_mv	AT zairakkumykova interpretationandsignificanceofthedefinitionofantimullerianhormoneinthepracticeofjuvenilegynaecologist AT elenavuvarova interpretationandsignificanceofthedefinitionofantimullerianhormoneinthepracticeofjuvenilegynaecologist AT zalinakbatyrova interpretationandsignificanceofthedefinitionofantimullerianhormoneinthepracticeofjuvenilegynaecologist
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Interpretation and significance of the definition of anti-Mullerian hormone in the practice of juvenile gynaecologist

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