Neuronal cell-subtype specificity of neural synchronization in mouse primary visual cortex
Synchronised neuronal activity is essential for cortical function, yet mechanistic insights into this process remain limited. Here, authors use a combination of in vivo imaging and targeted whole-cell recordings to demonstrate that Somatostatin neurons, in the superficial layers of the mouse primary...
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Nature Portfolio
2019
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oai:doaj.org-article:780bbc32604449c2ad1eb429dc554cf82021-12-02T14:39:57ZNeuronal cell-subtype specificity of neural synchronization in mouse primary visual cortex10.1038/s41467-019-10498-12041-1723https://doaj.org/article/780bbc32604449c2ad1eb429dc554cf82019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10498-1https://doaj.org/toc/2041-1723Synchronised neuronal activity is essential for cortical function, yet mechanistic insights into this process remain limited. Here, authors use a combination of in vivo imaging and targeted whole-cell recordings to demonstrate that Somatostatin neurons, in the superficial layers of the mouse primary visual cortex, exhibit functional heterogeneity and can be classified into two distinct subtypes characterized as either having type I uncorrelated, or type II highly correlated with network activity.Ulf KnoblichLawrence HuangHongkui ZengLu LiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019) |
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Science Q Ulf Knoblich Lawrence Huang Hongkui Zeng Lu Li Neuronal cell-subtype specificity of neural synchronization in mouse primary visual cortex |
description |
Synchronised neuronal activity is essential for cortical function, yet mechanistic insights into this process remain limited. Here, authors use a combination of in vivo imaging and targeted whole-cell recordings to demonstrate that Somatostatin neurons, in the superficial layers of the mouse primary visual cortex, exhibit functional heterogeneity and can be classified into two distinct subtypes characterized as either having type I uncorrelated, or type II highly correlated with network activity. |
format |
article |
author |
Ulf Knoblich Lawrence Huang Hongkui Zeng Lu Li |
author_facet |
Ulf Knoblich Lawrence Huang Hongkui Zeng Lu Li |
author_sort |
Ulf Knoblich |
title |
Neuronal cell-subtype specificity of neural synchronization in mouse primary visual cortex |
title_short |
Neuronal cell-subtype specificity of neural synchronization in mouse primary visual cortex |
title_full |
Neuronal cell-subtype specificity of neural synchronization in mouse primary visual cortex |
title_fullStr |
Neuronal cell-subtype specificity of neural synchronization in mouse primary visual cortex |
title_full_unstemmed |
Neuronal cell-subtype specificity of neural synchronization in mouse primary visual cortex |
title_sort |
neuronal cell-subtype specificity of neural synchronization in mouse primary visual cortex |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/780bbc32604449c2ad1eb429dc554cf8 |
work_keys_str_mv |
AT ulfknoblich neuronalcellsubtypespecificityofneuralsynchronizationinmouseprimaryvisualcortex AT lawrencehuang neuronalcellsubtypespecificityofneuralsynchronizationinmouseprimaryvisualcortex AT hongkuizeng neuronalcellsubtypespecificityofneuralsynchronizationinmouseprimaryvisualcortex AT luli neuronalcellsubtypespecificityofneuralsynchronizationinmouseprimaryvisualcortex |
_version_ |
1718390480995090432 |