Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development

Outer radial glial cells (oRGs) are undifferentiated cells that divide in the subventricular zone during neurodevelopment, but the underlying mechanisms are not fully understood. Here the authors show that Lzts1 positively controls both neuronal delamination and generation of oRG-like cell types.

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Autores principales:	T. Kawaue, A. Shitamukai, A. Nagasaka, Y. Tsunekawa, T. Shinoda, K. Saito, R. Terada, M. Bilgic, T. Miyata, F. Matsuzaki, A. Kawaguchi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/78107fc0828c4cbfa10df65bdabf7187
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spelling	oai:doaj.org-article:78107fc0828c4cbfa10df65bdabf71872021-12-02T14:40:00ZLzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development10.1038/s41467-019-10730-y2041-1723https://doaj.org/article/78107fc0828c4cbfa10df65bdabf71872019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10730-yhttps://doaj.org/toc/2041-1723Outer radial glial cells (oRGs) are undifferentiated cells that divide in the subventricular zone during neurodevelopment, but the underlying mechanisms are not fully understood. Here the authors show that Lzts1 positively controls both neuronal delamination and generation of oRG-like cell types.T. KawaueA. ShitamukaiA. NagasakaY. TsunekawaT. ShinodaK. SaitoR. TeradaM. BilgicT. MiyataF. MatsuzakiA. KawaguchiNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-18 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q T. Kawaue A. Shitamukai A. Nagasaka Y. Tsunekawa T. Shinoda K. Saito R. Terada M. Bilgic T. Miyata F. Matsuzaki A. Kawaguchi Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development
description	Outer radial glial cells (oRGs) are undifferentiated cells that divide in the subventricular zone during neurodevelopment, but the underlying mechanisms are not fully understood. Here the authors show that Lzts1 positively controls both neuronal delamination and generation of oRG-like cell types.
format	article
author	T. Kawaue A. Shitamukai A. Nagasaka Y. Tsunekawa T. Shinoda K. Saito R. Terada M. Bilgic T. Miyata F. Matsuzaki A. Kawaguchi
author_facet	T. Kawaue A. Shitamukai A. Nagasaka Y. Tsunekawa T. Shinoda K. Saito R. Terada M. Bilgic T. Miyata F. Matsuzaki A. Kawaguchi
author_sort	T. Kawaue
title	Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development
title_short	Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development
title_full	Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development
title_fullStr	Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development
title_full_unstemmed	Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development
title_sort	lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/78107fc0828c4cbfa10df65bdabf7187
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Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development

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