Early detection and staging of chronic liver diseases with a protein MRI contrast agent
Non-invasive early diagnosis of liver fibrosis is important to prevent disease progression and direct treatment strategies. Here the authors developed a collagen-targeting contrast agent for the detection of early stage fibrosis and non-alcoholic steatohepatitis by magnetic resonance and tested it i...
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Nature Portfolio
2019
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oai:doaj.org-article:7815a12c65474deb997bdf57a3b68b7b2021-12-02T14:38:44ZEarly detection and staging of chronic liver diseases with a protein MRI contrast agent10.1038/s41467-019-11984-22041-1723https://doaj.org/article/7815a12c65474deb997bdf57a3b68b7b2019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11984-2https://doaj.org/toc/2041-1723Non-invasive early diagnosis of liver fibrosis is important to prevent disease progression and direct treatment strategies. Here the authors developed a collagen-targeting contrast agent for the detection of early stage fibrosis and non-alcoholic steatohepatitis by magnetic resonance and tested it in animal models.Mani SalarianRavi Chakra TuragaShenghui XueMaysam NezafatiKhan HekmatyarJingjuan QiaoYinwei ZhangShanshan TanOluwatosin Y. IbhaguiYan HaiJibiao LiRao MukkavilliMalvika SharmaPardeep MittalXiaoyi MinShella KeilholzLiqing YuGengshen QinAlton Brad FarrisZhi-Ren LiuJenny J. YangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
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DOAJ |
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DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Mani Salarian Ravi Chakra Turaga Shenghui Xue Maysam Nezafati Khan Hekmatyar Jingjuan Qiao Yinwei Zhang Shanshan Tan Oluwatosin Y. Ibhagui Yan Hai Jibiao Li Rao Mukkavilli Malvika Sharma Pardeep Mittal Xiaoyi Min Shella Keilholz Liqing Yu Gengshen Qin Alton Brad Farris Zhi-Ren Liu Jenny J. Yang Early detection and staging of chronic liver diseases with a protein MRI contrast agent |
| description |
Non-invasive early diagnosis of liver fibrosis is important to prevent disease progression and direct treatment strategies. Here the authors developed a collagen-targeting contrast agent for the detection of early stage fibrosis and non-alcoholic steatohepatitis by magnetic resonance and tested it in animal models. |
| format |
article |
| author |
Mani Salarian Ravi Chakra Turaga Shenghui Xue Maysam Nezafati Khan Hekmatyar Jingjuan Qiao Yinwei Zhang Shanshan Tan Oluwatosin Y. Ibhagui Yan Hai Jibiao Li Rao Mukkavilli Malvika Sharma Pardeep Mittal Xiaoyi Min Shella Keilholz Liqing Yu Gengshen Qin Alton Brad Farris Zhi-Ren Liu Jenny J. Yang |
| author_facet |
Mani Salarian Ravi Chakra Turaga Shenghui Xue Maysam Nezafati Khan Hekmatyar Jingjuan Qiao Yinwei Zhang Shanshan Tan Oluwatosin Y. Ibhagui Yan Hai Jibiao Li Rao Mukkavilli Malvika Sharma Pardeep Mittal Xiaoyi Min Shella Keilholz Liqing Yu Gengshen Qin Alton Brad Farris Zhi-Ren Liu Jenny J. Yang |
| author_sort |
Mani Salarian |
| title |
Early detection and staging of chronic liver diseases with a protein MRI contrast agent |
| title_short |
Early detection and staging of chronic liver diseases with a protein MRI contrast agent |
| title_full |
Early detection and staging of chronic liver diseases with a protein MRI contrast agent |
| title_fullStr |
Early detection and staging of chronic liver diseases with a protein MRI contrast agent |
| title_full_unstemmed |
Early detection and staging of chronic liver diseases with a protein MRI contrast agent |
| title_sort |
early detection and staging of chronic liver diseases with a protein mri contrast agent |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/7815a12c65474deb997bdf57a3b68b7b |
| work_keys_str_mv |
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