A bioinspired scaffold for rapid oxygenation of cell encapsulation systems

Cell encapsulation into biomaterials for transplantation is currently limited by inadequate oxygenation. Here the authors present a biomimetic scaffold featuring internal continuous air channels endowed with 10,000-fold higher O2 diffusivity than hydrogels and demonstrate correction of diabetes in i...

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Autores principales:	Long-Hai Wang, Alexander Ulrich Ernst, Duo An, Ashim Kumar Datta, Boris Epel, Mrignayani Kotecha, Minglin Ma
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/781e0ecf93d24a7bb9d71476198c9510
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id	oai:doaj.org-article:781e0ecf93d24a7bb9d71476198c9510
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spelling	oai:doaj.org-article:781e0ecf93d24a7bb9d71476198c95102021-12-02T18:37:28ZA bioinspired scaffold for rapid oxygenation of cell encapsulation systems10.1038/s41467-021-26126-w2041-1723https://doaj.org/article/781e0ecf93d24a7bb9d71476198c95102021-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26126-whttps://doaj.org/toc/2041-1723Cell encapsulation into biomaterials for transplantation is currently limited by inadequate oxygenation. Here the authors present a biomimetic scaffold featuring internal continuous air channels endowed with 10,000-fold higher O2 diffusivity than hydrogels and demonstrate correction of diabetes in immunocompetent mice using rat islets for over 6 months.Long-Hai WangAlexander Ulrich ErnstDuo AnAshim Kumar DattaBoris EpelMrignayani KotechaMinglin MaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Long-Hai Wang Alexander Ulrich Ernst Duo An Ashim Kumar Datta Boris Epel Mrignayani Kotecha Minglin Ma A bioinspired scaffold for rapid oxygenation of cell encapsulation systems
description	Cell encapsulation into biomaterials for transplantation is currently limited by inadequate oxygenation. Here the authors present a biomimetic scaffold featuring internal continuous air channels endowed with 10,000-fold higher O2 diffusivity than hydrogels and demonstrate correction of diabetes in immunocompetent mice using rat islets for over 6 months.
format	article
author	Long-Hai Wang Alexander Ulrich Ernst Duo An Ashim Kumar Datta Boris Epel Mrignayani Kotecha Minglin Ma
author_facet	Long-Hai Wang Alexander Ulrich Ernst Duo An Ashim Kumar Datta Boris Epel Mrignayani Kotecha Minglin Ma
author_sort	Long-Hai Wang
title	A bioinspired scaffold for rapid oxygenation of cell encapsulation systems
title_short	A bioinspired scaffold for rapid oxygenation of cell encapsulation systems
title_full	A bioinspired scaffold for rapid oxygenation of cell encapsulation systems
title_fullStr	A bioinspired scaffold for rapid oxygenation of cell encapsulation systems
title_full_unstemmed	A bioinspired scaffold for rapid oxygenation of cell encapsulation systems
title_sort	bioinspired scaffold for rapid oxygenation of cell encapsulation systems
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/781e0ecf93d24a7bb9d71476198c9510
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A bioinspired scaffold for rapid oxygenation of cell encapsulation systems

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