Programmable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides

Here the authors show that disordered polypeptide-RNA condensates exhibit rheological properties similar to that of a viscoelastic Maxwell fluid, and use simple polypeptide design rules to create microcondensates with tunable viscoelasticity.

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Autores principales:	Ibraheem Alshareedah, Mahdi Muhammad Moosa, Matthew Pham, Davit A. Potoyan, Priya R. Banerjee
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/782d6587c7424a8ebfa032657b39f301
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spelling	oai:doaj.org-article:782d6587c7424a8ebfa032657b39f3012021-11-21T12:35:27ZProgrammable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides10.1038/s41467-021-26733-72041-1723https://doaj.org/article/782d6587c7424a8ebfa032657b39f3012021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26733-7https://doaj.org/toc/2041-1723Here the authors show that disordered polypeptide-RNA condensates exhibit rheological properties similar to that of a viscoelastic Maxwell fluid, and use simple polypeptide design rules to create microcondensates with tunable viscoelasticity.Ibraheem AlshareedahMahdi Muhammad MoosaMatthew PhamDavit A. PotoyanPriya R. BanerjeeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ibraheem Alshareedah Mahdi Muhammad Moosa Matthew Pham Davit A. Potoyan Priya R. Banerjee Programmable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides
description	Here the authors show that disordered polypeptide-RNA condensates exhibit rheological properties similar to that of a viscoelastic Maxwell fluid, and use simple polypeptide design rules to create microcondensates with tunable viscoelasticity.
format	article
author	Ibraheem Alshareedah Mahdi Muhammad Moosa Matthew Pham Davit A. Potoyan Priya R. Banerjee
author_facet	Ibraheem Alshareedah Mahdi Muhammad Moosa Matthew Pham Davit A. Potoyan Priya R. Banerjee
author_sort	Ibraheem Alshareedah
title	Programmable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides
title_short	Programmable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides
title_full	Programmable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides
title_fullStr	Programmable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides
title_full_unstemmed	Programmable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides
title_sort	programmable viscoelasticity in protein-rna condensates with disordered sticker-spacer polypeptides
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/782d6587c7424a8ebfa032657b39f301
work_keys_str_mv	AT ibraheemalshareedah programmableviscoelasticityinproteinrnacondensateswithdisorderedstickerspacerpolypeptides AT mahdimuhammadmoosa programmableviscoelasticityinproteinrnacondensateswithdisorderedstickerspacerpolypeptides AT matthewpham programmableviscoelasticityinproteinrnacondensateswithdisorderedstickerspacerpolypeptides AT davitapotoyan programmableviscoelasticityinproteinrnacondensateswithdisorderedstickerspacerpolypeptides AT priyarbanerjee programmableviscoelasticityinproteinrnacondensateswithdisorderedstickerspacerpolypeptides
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Programmable viscoelasticity in protein-RNA condensates with disordered sticker-spacer polypeptides

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