QUANTITATIVE EXPRESSION FEATURES OF PD-1 AND TIM-3 CHECKPOINT MOLECULE RECEPTORS ON CD4⁺ AND CD8⁺ T-CELLS IN BREAST CANCER OF VARYING PROGRESSION DEGREES
During the course of chronic viral infections or tumor growth, due to the constant presence of antigen and inflammation, a dysfunctional state of T-cells called exhaustion occurs. Factors associated with T-cell exhaustion include an increase in the expression of various inhibitory receptors, also kn...
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Autores principales: | Yu. A. Shevchenko, M. S. Kuznetsova, Yu. N. Khantakova, I. A. Obleukhova, A. A. Khristin, S. V. Sidorov, S. V. Sennikov |
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Formato: | article |
Lenguaje: | RU |
Publicado: |
SPb RAACI
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/78337c16a45142b5a553408888f419da |
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