Multiple DSB Resection Activities Redundantly Promote Alternative End Joining-Mediated Class Switch Recombination
Alternative end joining (A-EJ) catalyzes substantial level of antibody class switch recombination (CSR) in B cells deficient for classical non-homologous end joining, featuring increased switch (S) region DSB resection and junctional microhomology (MH). While resection has been suggested to initiate...
Guardado en:
Autores principales: | Xikui Sun, Jingning Bai, Jiejie Xu, Xiaoli Xi, Mingyu Gu, Chengming Zhu, Hongman Xue, Chun Chen, Junchao Dong |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/783e94bec6534c0ba59ab903e0bf080f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Involvement of classic and alternative non-homologous end joining pathways in hematologic malignancies: targeting strategies for treatment
por: Mohsen Valikhani, et al.
Publicado: (2021) -
Development of a CRISPR-Cas9 System for Efficient Genome Editing of <named-content content-type="genus-species">Candida lusitaniae</named-content>
por: Emily L. Norton, et al.
Publicado: (2017) -
LigD: A Structural Guide to the Multi-Tool of Bacterial Non-Homologous End Joining
por: Benhur Amare, et al.
Publicado: (2021) -
Genomic Instability and Cancer Risk Associated with Erroneous DNA Repair
por: Ken-ichi Yoshioka, et al.
Publicado: (2021) -
A CRISPR-Assisted Nonhomologous End-Joining Strategy for Efficient Genome Editing in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>
por: Mei-Yi Yan, et al.
Publicado: (2020)