Cell-free 3D scaffold with two-stage delivery of miRNA-26a to regenerate critical-sized bone defects
A challenge in regenerative medicine is the development of cell-free, non-immunogenic miRNA-delivering scaffolds. Here the authors design a cell-free scaffold capable of efficient and prolonged delivery of miRNA-26a to endogenous cells and show that it can regenerate a full-thickness calvarial bone...
Enregistré dans:
Auteurs principaux: | Xiaojin Zhang, Yan Li, Y. Eugene Chen, Jihua Chen, Peter X. Ma |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2016
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/783ff9bf6ea14f57b75bbdaad033b2ec |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
In vivo experimental study on bone regeneration in critical bone defects using PIB nanogels/boron-containing mesoporous bioactive glass composite scaffold
par: Chen XH, et autres
Publié: (2015) -
Local administration of HMGB-1 promotes bone regeneration on the critical-sized mandibular defects in rabbits
par: Ahmed Monir, et autres
Publié: (2021) -
Comparative study of porous hydroxyapatite/chitosan and whitlockite/chitosan scaffolds for bone regeneration in calvarial defects
par: Zhou D, et autres
Publié: (2017) -
Injectable hybrid system for strontium local delivery promotes bone regeneration in a rat critical-sized defect model
par: Ana Henriques Lourenço, et autres
Publié: (2017) -
Angiogenesis and bone regeneration of porous nano-hydroxyapatite/coralline blocks coated with rhVEGF165 in critical-size alveolar bone defects in vivo
par: Du B, et autres
Publié: (2015)