Risperidone-induced reversible neutropenia

Vasanth Kattalai Kailasam,1 Victoria Chima,2,* Uchechukwu Nnamdi,3,* Kavita Sharma,4,* Kairav Shah5 1College of Medicine, University of Illinois, Chicago, IL, USA; 2Mount Sinai Beth Israel Medical Center, New York, NY, USA; 3Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY,...

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Autores principales: Kattalai Kailasam V, Chima V, Nnamdi U, Sharma K, Shah K
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Lenguaje:EN
Publicado: Dove Medical Press 2017
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spelling oai:doaj.org-article:7849e47eedbe4eb3a8477b780276af202021-12-02T03:24:55ZRisperidone-induced reversible neutropenia1178-2021https://doaj.org/article/7849e47eedbe4eb3a8477b780276af202017-07-01T00:00:00Zhttps://www.dovepress.com/risperidone-induced-reversible-neutropenia-peer-reviewed-article-NDThttps://doaj.org/toc/1178-2021Vasanth Kattalai Kailasam,1 Victoria Chima,2,* Uchechukwu Nnamdi,3,* Kavita Sharma,4,* Kairav Shah5 1College of Medicine, University of Illinois, Chicago, IL, USA; 2Mount Sinai Beth Israel Medical Center, New York, NY, USA; 3Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, USA; 4Harlem Hospital Center, New York, NY, USA; 5Department of Psychiatry & Behavioral Sciences, The University of Texas McGovern Medical School, Houston, TX, USA *These authors contributed equally to this work Abstract: This case report presents a 44-year-old man with a history of schizophrenia who developed neutropenia on risperidone therapy. The patient’s laboratory reports showed a gradual decline of leukocytes and neutrophils after resolution and rechallenging. This was reversed with the discontinuation of risperidone and by switching to olanzapine. In this case report, we also discuss the updated evidence base for management of risperidone-induced neutropenia. Keywords: risperidone, antipsychotics, neutropenia, blood dyscrasias Kattalai Kailasam VChima VNnamdi USharma KShah KDove Medical Pressarticlerisperidoneanti-psychoticsneutropeniablood dyscrasiasNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol Volume 13, Pp 1975-1977 (2017)
institution DOAJ
collection DOAJ
language EN
topic risperidone
anti-psychotics
neutropenia
blood dyscrasias
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
spellingShingle risperidone
anti-psychotics
neutropenia
blood dyscrasias
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Neurology. Diseases of the nervous system
RC346-429
Kattalai Kailasam V
Chima V
Nnamdi U
Sharma K
Shah K
Risperidone-induced reversible neutropenia
description Vasanth Kattalai Kailasam,1 Victoria Chima,2,* Uchechukwu Nnamdi,3,* Kavita Sharma,4,* Kairav Shah5 1College of Medicine, University of Illinois, Chicago, IL, USA; 2Mount Sinai Beth Israel Medical Center, New York, NY, USA; 3Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY, USA; 4Harlem Hospital Center, New York, NY, USA; 5Department of Psychiatry & Behavioral Sciences, The University of Texas McGovern Medical School, Houston, TX, USA *These authors contributed equally to this work Abstract: This case report presents a 44-year-old man with a history of schizophrenia who developed neutropenia on risperidone therapy. The patient’s laboratory reports showed a gradual decline of leukocytes and neutrophils after resolution and rechallenging. This was reversed with the discontinuation of risperidone and by switching to olanzapine. In this case report, we also discuss the updated evidence base for management of risperidone-induced neutropenia. Keywords: risperidone, antipsychotics, neutropenia, blood dyscrasias 
format article
author Kattalai Kailasam V
Chima V
Nnamdi U
Sharma K
Shah K
author_facet Kattalai Kailasam V
Chima V
Nnamdi U
Sharma K
Shah K
author_sort Kattalai Kailasam V
title Risperidone-induced reversible neutropenia
title_short Risperidone-induced reversible neutropenia
title_full Risperidone-induced reversible neutropenia
title_fullStr Risperidone-induced reversible neutropenia
title_full_unstemmed Risperidone-induced reversible neutropenia
title_sort risperidone-induced reversible neutropenia
publisher Dove Medical Press
publishDate 2017
url https://doaj.org/article/7849e47eedbe4eb3a8477b780276af20
work_keys_str_mv AT kattalaikailasamv risperidoneinducedreversibleneutropenia
AT chimav risperidoneinducedreversibleneutropenia
AT nnamdiu risperidoneinducedreversibleneutropenia
AT sharmak risperidoneinducedreversibleneutropenia
AT shahk risperidoneinducedreversibleneutropenia
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