Pulsatile Bi-Directional Aerosol Flow Affects Aerosol Delivery to the Intranasal Olfactory Region: A Patient-Specific Computational Study

The nasal olfactory region is a potential route for non-invasive delivery of drugs directly from the nasal epithelium to the brain, bypassing the often impermeable blood-brain barrier. However, efficient aerosol delivery to the olfactory region is challenging due to its location in the nose. Here we...

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Autores principales: Ali Farnoud, Hesam Tofighian, Ingo Baumann, Andrew R. Martin, Mohammad M. Rashidi, Micheal P. Menden, Otmar Schmid
Formato: article
Lenguaje:EN
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://doaj.org/article/784ad23d6aaa41f3aeffb11bd26bc5d2
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