Tissue‐Specific Regulation of Ferroportin in Wild‐Type and Hjv‐/‐ Mice Following Dietary Iron Manipulations
Hepcidin is a liver‐derived peptide hormone that limits iron egress from tissues to the bloodstream. It operates by binding to the iron exporter ferroportin, which blocks iron transport and tags ferroportin for degradation. Genetic hepcidin inactivation leads to hereditary hemochromatosis, a disease...
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| Format: | article |
| Langue: | EN |
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Wiley
2021
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| Accès en ligne: | https://doaj.org/article/784ef1e3ba9a41588b921c36f160bff0 |
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