Dkk1 regulates ventral midbrain dopaminergic differentiation and morphogenesis.

Dickkopf1 (Dkk1) is a Wnt/β-catenin inhibitor that participates in many processes during embryonic development. One of its roles during embryogenesis is to induce head formation, since Dkk1-null mice lack head structures anterior to midbrain. The Wnt/β-catenin pathway is also known to regulate diffe...

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Autores principales: Diogo Ribeiro, Kristina Ellwanger, Désirée Glagow, Spyridon Theofilopoulos, Nina S Corsini, Ana Martin-Villalba, Christof Niehrs, Ernest Arenas
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/785d671a481e489f97a8a2fdd6913b71
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