The Effects of Salt Concentration on the Rejection of Pharmaceutically Active Compounds by Nanofiltration Membranes

While traces of pharmaceuticals have been found in the environment, the pharmaceutical industry produces waste streams high in pharmaceutically active compounds concentration along with other components such as salts. This work investigated the removal of three common pharmaceuticals, carbamazepine,...

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Autores principales: Hadi M. Kabbani, Mahmoud Al-Hindi, George M. Ayoub, Mohammad N. Ahmad
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Lenguaje:EN
Publicado: SDEWES Centre 2021
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spelling oai:doaj.org-article:785ec601010a41a7af0e2b575dcd4e4e2021-11-20T09:32:48ZThe Effects of Salt Concentration on the Rejection of Pharmaceutically Active Compounds by Nanofiltration Membranes1848-925710.13044/j.sdewes.d8.0356https://doaj.org/article/785ec601010a41a7af0e2b575dcd4e4e2021-09-01T00:00:00Z http://www.sdewes.org/jsdewes/pid8.0356 https://doaj.org/toc/1848-9257While traces of pharmaceuticals have been found in the environment, the pharmaceutical industry produces waste streams high in pharmaceutically active compounds concentration along with other components such as salts. This work investigated the removal of three common pharmaceuticals, carbamazepine, ibuprofen, and diclofenac, at concentrations found in the pharmaceutical industry, under different monovalent salt concentrations of sodium chloride using a commercially available nanofiltration membrane. The influence of a monovalent salt concentration and temperature on the removal were determined. Pharmaceutical rejection was found to be dependent on the compounds’ molecular weights, charge, and hydrophobicity. Diclofenac and ibuprofen rejections were found to be high (90-99%) and (85-96%) respectively, and the rejection increased with increasing salt concentration. Meanwhile, moderate retention values were found for the neutral carbamazepine (65-77%) and these values decreased with increasing salt concentration, and also decreased with increasing temperatures. A threshold salt concentration was found at which these effects were buffered or even reversed.Hadi M. KabbaniMahmoud Al-HindiGeorge M. AyoubMohammad N. AhmadSDEWES Centrearticlemembranesnanofiltrationpharmaceuticalsenvironmentsalttemperature.TechnologyTEconomic growth, development, planningHD72-88ENJournal of Sustainable Development of Energy, Water and Environment Systems, Vol 9, Iss 3, Pp 1-16 (2021)
institution DOAJ
collection DOAJ
language EN
topic membranes
nanofiltration
pharmaceuticals
environment
salt
temperature.
Technology
T
Economic growth, development, planning
HD72-88
spellingShingle membranes
nanofiltration
pharmaceuticals
environment
salt
temperature.
Technology
T
Economic growth, development, planning
HD72-88
Hadi M. Kabbani
Mahmoud Al-Hindi
George M. Ayoub
Mohammad N. Ahmad
The Effects of Salt Concentration on the Rejection of Pharmaceutically Active Compounds by Nanofiltration Membranes
description While traces of pharmaceuticals have been found in the environment, the pharmaceutical industry produces waste streams high in pharmaceutically active compounds concentration along with other components such as salts. This work investigated the removal of three common pharmaceuticals, carbamazepine, ibuprofen, and diclofenac, at concentrations found in the pharmaceutical industry, under different monovalent salt concentrations of sodium chloride using a commercially available nanofiltration membrane. The influence of a monovalent salt concentration and temperature on the removal were determined. Pharmaceutical rejection was found to be dependent on the compounds’ molecular weights, charge, and hydrophobicity. Diclofenac and ibuprofen rejections were found to be high (90-99%) and (85-96%) respectively, and the rejection increased with increasing salt concentration. Meanwhile, moderate retention values were found for the neutral carbamazepine (65-77%) and these values decreased with increasing salt concentration, and also decreased with increasing temperatures. A threshold salt concentration was found at which these effects were buffered or even reversed.
format article
author Hadi M. Kabbani
Mahmoud Al-Hindi
George M. Ayoub
Mohammad N. Ahmad
author_facet Hadi M. Kabbani
Mahmoud Al-Hindi
George M. Ayoub
Mohammad N. Ahmad
author_sort Hadi M. Kabbani
title The Effects of Salt Concentration on the Rejection of Pharmaceutically Active Compounds by Nanofiltration Membranes
title_short The Effects of Salt Concentration on the Rejection of Pharmaceutically Active Compounds by Nanofiltration Membranes
title_full The Effects of Salt Concentration on the Rejection of Pharmaceutically Active Compounds by Nanofiltration Membranes
title_fullStr The Effects of Salt Concentration on the Rejection of Pharmaceutically Active Compounds by Nanofiltration Membranes
title_full_unstemmed The Effects of Salt Concentration on the Rejection of Pharmaceutically Active Compounds by Nanofiltration Membranes
title_sort effects of salt concentration on the rejection of pharmaceutically active compounds by nanofiltration membranes
publisher SDEWES Centre
publishDate 2021
url https://doaj.org/article/785ec601010a41a7af0e2b575dcd4e4e
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