Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers

Abstract Enteric bacteria and/or their products are necessary for doxorubicin (DXR)-induced small intestine mucosal damage. While DXR does not induce gross loss of epithelium, others have shown elevated serum endotoxin after DXR administration. However, the mechanism of movement is unknown. We hypot...

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Autores principales: Paul Cray, Breanna J. Sheahan, Jocsa E. Cortes, Christopher M. Dekaney
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/78603ac7a081400ca719e9c2c2854856
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