A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex
The Nup82–Nup159–Nsp1 complex, which plays a key role in mRNA export, is recruited late during the process of nuclear pore complex (NPC) assembly. Here the authors combine crosslinking mass spectrometry, biochemical reconstitution and molecular modeling to gain insights into the mechanism of Nup82 r...
Guardado en:
Autores principales: | , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/78609ff12d0b48928339246d519bd94b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:78609ff12d0b48928339246d519bd94b |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:78609ff12d0b48928339246d519bd94b2021-12-02T14:40:49ZA short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex10.1038/s41467-017-01160-92041-1723https://doaj.org/article/78609ff12d0b48928339246d519bd94b2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01160-9https://doaj.org/toc/2041-1723The Nup82–Nup159–Nsp1 complex, which plays a key role in mRNA export, is recruited late during the process of nuclear pore complex (NPC) assembly. Here the authors combine crosslinking mass spectrometry, biochemical reconstitution and molecular modeling to gain insights into the mechanism of Nup82 recruitment to the NPC.Roman TeimerJan KosinskiAlexander von AppenMartin BeckEd HurtNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Roman Teimer Jan Kosinski Alexander von Appen Martin Beck Ed Hurt A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex |
description |
The Nup82–Nup159–Nsp1 complex, which plays a key role in mRNA export, is recruited late during the process of nuclear pore complex (NPC) assembly. Here the authors combine crosslinking mass spectrometry, biochemical reconstitution and molecular modeling to gain insights into the mechanism of Nup82 recruitment to the NPC. |
format |
article |
author |
Roman Teimer Jan Kosinski Alexander von Appen Martin Beck Ed Hurt |
author_facet |
Roman Teimer Jan Kosinski Alexander von Appen Martin Beck Ed Hurt |
author_sort |
Roman Teimer |
title |
A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex |
title_short |
A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex |
title_full |
A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex |
title_fullStr |
A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex |
title_full_unstemmed |
A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex |
title_sort |
short linear motif in scaffold nup145c connects y-complex with pre-assembled outer ring nup82 complex |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/78609ff12d0b48928339246d519bd94b |
work_keys_str_mv |
AT romanteimer ashortlinearmotifinscaffoldnup145cconnectsycomplexwithpreassembledouterringnup82complex AT jankosinski ashortlinearmotifinscaffoldnup145cconnectsycomplexwithpreassembledouterringnup82complex AT alexandervonappen ashortlinearmotifinscaffoldnup145cconnectsycomplexwithpreassembledouterringnup82complex AT martinbeck ashortlinearmotifinscaffoldnup145cconnectsycomplexwithpreassembledouterringnup82complex AT edhurt ashortlinearmotifinscaffoldnup145cconnectsycomplexwithpreassembledouterringnup82complex AT romanteimer shortlinearmotifinscaffoldnup145cconnectsycomplexwithpreassembledouterringnup82complex AT jankosinski shortlinearmotifinscaffoldnup145cconnectsycomplexwithpreassembledouterringnup82complex AT alexandervonappen shortlinearmotifinscaffoldnup145cconnectsycomplexwithpreassembledouterringnup82complex AT martinbeck shortlinearmotifinscaffoldnup145cconnectsycomplexwithpreassembledouterringnup82complex AT edhurt shortlinearmotifinscaffoldnup145cconnectsycomplexwithpreassembledouterringnup82complex |
_version_ |
1718390119450279936 |