A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex

The Nup82–Nup159–Nsp1 complex, which plays a key role in mRNA export, is recruited late during the process of nuclear pore complex (NPC) assembly. Here the authors combine crosslinking mass spectrometry, biochemical reconstitution and molecular modeling to gain insights into the mechanism of Nup82 r...

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Autores principales: Roman Teimer, Jan Kosinski, Alexander von Appen, Martin Beck, Ed Hurt
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/78609ff12d0b48928339246d519bd94b
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spelling oai:doaj.org-article:78609ff12d0b48928339246d519bd94b2021-12-02T14:40:49ZA short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex10.1038/s41467-017-01160-92041-1723https://doaj.org/article/78609ff12d0b48928339246d519bd94b2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01160-9https://doaj.org/toc/2041-1723The Nup82–Nup159–Nsp1 complex, which plays a key role in mRNA export, is recruited late during the process of nuclear pore complex (NPC) assembly. Here the authors combine crosslinking mass spectrometry, biochemical reconstitution and molecular modeling to gain insights into the mechanism of Nup82 recruitment to the NPC.Roman TeimerJan KosinskiAlexander von AppenMartin BeckEd HurtNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Roman Teimer
Jan Kosinski
Alexander von Appen
Martin Beck
Ed Hurt
A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex
description The Nup82–Nup159–Nsp1 complex, which plays a key role in mRNA export, is recruited late during the process of nuclear pore complex (NPC) assembly. Here the authors combine crosslinking mass spectrometry, biochemical reconstitution and molecular modeling to gain insights into the mechanism of Nup82 recruitment to the NPC.
format article
author Roman Teimer
Jan Kosinski
Alexander von Appen
Martin Beck
Ed Hurt
author_facet Roman Teimer
Jan Kosinski
Alexander von Appen
Martin Beck
Ed Hurt
author_sort Roman Teimer
title A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex
title_short A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex
title_full A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex
title_fullStr A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex
title_full_unstemmed A short linear motif in scaffold Nup145C connects Y-complex with pre-assembled outer ring Nup82 complex
title_sort short linear motif in scaffold nup145c connects y-complex with pre-assembled outer ring nup82 complex
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/78609ff12d0b48928339246d519bd94b
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