Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress

Cellular extrinsic environmental factors contribute to tumour development. Here, the authors show that gastric acid stress stimulates tumour formation from a defined tumour-competent Krt5 + /Krt15 + foregut basal progenitor cell population.

Guardado en:

Detalles Bibliográficos
Autores principales:	Hyeongsun Moon, Jerry Zhu, Leanne R. Donahue, Eunju Choi, Andrew C. White
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7869f89b2952464bb4c94fa9d186093f
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:7869f89b2952464bb4c94fa9d186093f
record_format	dspace
spelling	oai:doaj.org-article:7869f89b2952464bb4c94fa9d186093f2021-12-02T17:02:10ZKrt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress10.1038/s41467-019-10194-02041-1723https://doaj.org/article/7869f89b2952464bb4c94fa9d186093f2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10194-0https://doaj.org/toc/2041-1723Cellular extrinsic environmental factors contribute to tumour development. Here, the authors show that gastric acid stress stimulates tumour formation from a defined tumour-competent Krt5 + /Krt15 + foregut basal progenitor cell population.Hyeongsun MoonJerry ZhuLeanne R. DonahueEunju ChoiAndrew C. WhiteNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hyeongsun Moon Jerry Zhu Leanne R. Donahue Eunju Choi Andrew C. White Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress
description	Cellular extrinsic environmental factors contribute to tumour development. Here, the authors show that gastric acid stress stimulates tumour formation from a defined tumour-competent Krt5 + /Krt15 + foregut basal progenitor cell population.
format	article
author	Hyeongsun Moon Jerry Zhu Leanne R. Donahue Eunju Choi Andrew C. White
author_facet	Hyeongsun Moon Jerry Zhu Leanne R. Donahue Eunju Choi Andrew C. White
author_sort	Hyeongsun Moon
title	Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress
title_short	Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress
title_full	Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress
title_fullStr	Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress
title_full_unstemmed	Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress
title_sort	krt5+/krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/7869f89b2952464bb4c94fa9d186093f
work_keys_str_mv	AT hyeongsunmoon krt5krt15foregutbasalprogenitorsgiverisetocyclooxygenase2dependenttumoursinresponsetogastricacidstress AT jerryzhu krt5krt15foregutbasalprogenitorsgiverisetocyclooxygenase2dependenttumoursinresponsetogastricacidstress AT leannerdonahue krt5krt15foregutbasalprogenitorsgiverisetocyclooxygenase2dependenttumoursinresponsetogastricacidstress AT eunjuchoi krt5krt15foregutbasalprogenitorsgiverisetocyclooxygenase2dependenttumoursinresponsetogastricacidstress AT andrewcwhite krt5krt15foregutbasalprogenitorsgiverisetocyclooxygenase2dependenttumoursinresponsetogastricacidstress
_version_	1718381976405147648

Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress

Ejemplares similares