Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress
Cellular extrinsic environmental factors contribute to tumour development. Here, the authors show that gastric acid stress stimulates tumour formation from a defined tumour-competent Krt5 + /Krt15 + foregut basal progenitor cell population.
Guardado en:
Autores principales: | , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7869f89b2952464bb4c94fa9d186093f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:7869f89b2952464bb4c94fa9d186093f |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:7869f89b2952464bb4c94fa9d186093f2021-12-02T17:02:10ZKrt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress10.1038/s41467-019-10194-02041-1723https://doaj.org/article/7869f89b2952464bb4c94fa9d186093f2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10194-0https://doaj.org/toc/2041-1723Cellular extrinsic environmental factors contribute to tumour development. Here, the authors show that gastric acid stress stimulates tumour formation from a defined tumour-competent Krt5 + /Krt15 + foregut basal progenitor cell population.Hyeongsun MoonJerry ZhuLeanne R. DonahueEunju ChoiAndrew C. WhiteNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Hyeongsun Moon Jerry Zhu Leanne R. Donahue Eunju Choi Andrew C. White Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress |
description |
Cellular extrinsic environmental factors contribute to tumour development. Here, the authors show that gastric acid stress stimulates tumour formation from a defined tumour-competent Krt5 + /Krt15 + foregut basal progenitor cell population. |
format |
article |
author |
Hyeongsun Moon Jerry Zhu Leanne R. Donahue Eunju Choi Andrew C. White |
author_facet |
Hyeongsun Moon Jerry Zhu Leanne R. Donahue Eunju Choi Andrew C. White |
author_sort |
Hyeongsun Moon |
title |
Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress |
title_short |
Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress |
title_full |
Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress |
title_fullStr |
Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress |
title_full_unstemmed |
Krt5+/Krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress |
title_sort |
krt5+/krt15+ foregut basal progenitors give rise to cyclooxygenase-2-dependent tumours in response to gastric acid stress |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/7869f89b2952464bb4c94fa9d186093f |
work_keys_str_mv |
AT hyeongsunmoon krt5krt15foregutbasalprogenitorsgiverisetocyclooxygenase2dependenttumoursinresponsetogastricacidstress AT jerryzhu krt5krt15foregutbasalprogenitorsgiverisetocyclooxygenase2dependenttumoursinresponsetogastricacidstress AT leannerdonahue krt5krt15foregutbasalprogenitorsgiverisetocyclooxygenase2dependenttumoursinresponsetogastricacidstress AT eunjuchoi krt5krt15foregutbasalprogenitorsgiverisetocyclooxygenase2dependenttumoursinresponsetogastricacidstress AT andrewcwhite krt5krt15foregutbasalprogenitorsgiverisetocyclooxygenase2dependenttumoursinresponsetogastricacidstress |
_version_ |
1718381976405147648 |