Near quantitative synthesis of urea macrocycles enabled by bulky N-substituent

Macrocycles are molecular structures extensively used in the design of catalysts, therapeutics and supramolecular assemblies but synthesis procedures that can produce macrocycles in high yield under high reaction concentrations are rare. Here the authors report the use of dynamic hindered urea bond...

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Autores principales:	Yingfeng Yang, Hanze Ying, Zhixia Li, Jiang Wang, Yingying Chen, Binbin Luo, Danielle L. Gray, Andrew Ferguson, Qian Chen, Y. Z, Jianjun Cheng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/787290b568cd4e2da9c4a5349f34da43
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spelling	oai:doaj.org-article:787290b568cd4e2da9c4a5349f34da432021-12-02T13:34:48ZNear quantitative synthesis of urea macrocycles enabled by bulky N-substituent10.1038/s41467-021-21678-32041-1723https://doaj.org/article/787290b568cd4e2da9c4a5349f34da432021-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21678-3https://doaj.org/toc/2041-1723Macrocycles are molecular structures extensively used in the design of catalysts, therapeutics and supramolecular assemblies but synthesis procedures that can produce macrocycles in high yield under high reaction concentrations are rare. Here the authors report the use of dynamic hindered urea bond for the construction of urea macrocycles with high efficiency.Yingfeng YangHanze YingZhixia LiJiang WangYingying ChenBinbin LuoDanielle L. GrayAndrew FergusonQian ChenY. ZJianjun ChengNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yingfeng Yang Hanze Ying Zhixia Li Jiang Wang Yingying Chen Binbin Luo Danielle L. Gray Andrew Ferguson Qian Chen Y. Z Jianjun Cheng Near quantitative synthesis of urea macrocycles enabled by bulky N-substituent
description	Macrocycles are molecular structures extensively used in the design of catalysts, therapeutics and supramolecular assemblies but synthesis procedures that can produce macrocycles in high yield under high reaction concentrations are rare. Here the authors report the use of dynamic hindered urea bond for the construction of urea macrocycles with high efficiency.
format	article
author	Yingfeng Yang Hanze Ying Zhixia Li Jiang Wang Yingying Chen Binbin Luo Danielle L. Gray Andrew Ferguson Qian Chen Y. Z Jianjun Cheng
author_facet	Yingfeng Yang Hanze Ying Zhixia Li Jiang Wang Yingying Chen Binbin Luo Danielle L. Gray Andrew Ferguson Qian Chen Y. Z Jianjun Cheng
author_sort	Yingfeng Yang
title	Near quantitative synthesis of urea macrocycles enabled by bulky N-substituent
title_short	Near quantitative synthesis of urea macrocycles enabled by bulky N-substituent
title_full	Near quantitative synthesis of urea macrocycles enabled by bulky N-substituent
title_fullStr	Near quantitative synthesis of urea macrocycles enabled by bulky N-substituent
title_full_unstemmed	Near quantitative synthesis of urea macrocycles enabled by bulky N-substituent
title_sort	near quantitative synthesis of urea macrocycles enabled by bulky n-substituent
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/787290b568cd4e2da9c4a5349f34da43
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Near quantitative synthesis of urea macrocycles enabled by bulky N-substituent

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