Transcriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons

Little is known about von Economo neurons, which have been described in a subset of mammals and appear to be selectively lost in several human neurological diseases. Here, authors reveal the gene expression profile of these cells and show that they are likely long-distance projection neurons.

Guardado en:

Detalles Bibliográficos
Autores principales:	Rebecca D. Hodge, Jeremy A. Miller, Mark Novotny, Brian E. Kalmbach, Jonathan T. Ting, Trygve E. Bakken, Brian D. Aevermann, Eliza R. Barkan, Madeline L. Berkowitz-Cerasano, Charles Cobbs, Francisco Diez-Fuertes, Song-Lin Ding, Jamison McCorrison, Nicholas J. Schork, Soraya I. Shehata, Kimberly A. Smith, Susan M. Sunkin, Danny N. Tran, Pratap Venepally, Anna Marie Yanny, Frank J. Steemers, John W. Phillips, Amy Bernard, Christof Koch, Roger S. Lasken, Richard H. Scheuermann, Ed S. Lein
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/78763ec182d74a1e969da1bbe56703f2
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:78763ec182d74a1e969da1bbe56703f2
record_format	dspace
spelling	oai:doaj.org-article:78763ec182d74a1e969da1bbe56703f22021-12-02T15:37:18ZTranscriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons10.1038/s41467-020-14952-32041-1723https://doaj.org/article/78763ec182d74a1e969da1bbe56703f22020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14952-3https://doaj.org/toc/2041-1723Little is known about von Economo neurons, which have been described in a subset of mammals and appear to be selectively lost in several human neurological diseases. Here, authors reveal the gene expression profile of these cells and show that they are likely long-distance projection neurons.Rebecca D. HodgeJeremy A. MillerMark NovotnyBrian E. KalmbachJonathan T. TingTrygve E. BakkenBrian D. AevermannEliza R. BarkanMadeline L. Berkowitz-CerasanoCharles CobbsFrancisco Diez-FuertesSong-Lin DingJamison McCorrisonNicholas J. SchorkSoraya I. ShehataKimberly A. SmithSusan M. SunkinDanny N. TranPratap VenepallyAnna Marie YannyFrank J. SteemersJohn W. PhillipsAmy BernardChristof KochRoger S. LaskenRichard H. ScheuermannEd S. LeinNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Rebecca D. Hodge Jeremy A. Miller Mark Novotny Brian E. Kalmbach Jonathan T. Ting Trygve E. Bakken Brian D. Aevermann Eliza R. Barkan Madeline L. Berkowitz-Cerasano Charles Cobbs Francisco Diez-Fuertes Song-Lin Ding Jamison McCorrison Nicholas J. Schork Soraya I. Shehata Kimberly A. Smith Susan M. Sunkin Danny N. Tran Pratap Venepally Anna Marie Yanny Frank J. Steemers John W. Phillips Amy Bernard Christof Koch Roger S. Lasken Richard H. Scheuermann Ed S. Lein Transcriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons
description	Little is known about von Economo neurons, which have been described in a subset of mammals and appear to be selectively lost in several human neurological diseases. Here, authors reveal the gene expression profile of these cells and show that they are likely long-distance projection neurons.
format	article
author	Rebecca D. Hodge Jeremy A. Miller Mark Novotny Brian E. Kalmbach Jonathan T. Ting Trygve E. Bakken Brian D. Aevermann Eliza R. Barkan Madeline L. Berkowitz-Cerasano Charles Cobbs Francisco Diez-Fuertes Song-Lin Ding Jamison McCorrison Nicholas J. Schork Soraya I. Shehata Kimberly A. Smith Susan M. Sunkin Danny N. Tran Pratap Venepally Anna Marie Yanny Frank J. Steemers John W. Phillips Amy Bernard Christof Koch Roger S. Lasken Richard H. Scheuermann Ed S. Lein
author_facet	Rebecca D. Hodge Jeremy A. Miller Mark Novotny Brian E. Kalmbach Jonathan T. Ting Trygve E. Bakken Brian D. Aevermann Eliza R. Barkan Madeline L. Berkowitz-Cerasano Charles Cobbs Francisco Diez-Fuertes Song-Lin Ding Jamison McCorrison Nicholas J. Schork Soraya I. Shehata Kimberly A. Smith Susan M. Sunkin Danny N. Tran Pratap Venepally Anna Marie Yanny Frank J. Steemers John W. Phillips Amy Bernard Christof Koch Roger S. Lasken Richard H. Scheuermann Ed S. Lein
author_sort	Rebecca D. Hodge
title	Transcriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons
title_short	Transcriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons
title_full	Transcriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons
title_fullStr	Transcriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons
title_full_unstemmed	Transcriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons
title_sort	transcriptomic evidence that von economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/78763ec182d74a1e969da1bbe56703f2
work_keys_str_mv	AT rebeccadhodge transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT jeremyamiller transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT marknovotny transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT brianekalmbach transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT jonathantting transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT trygveebakken transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT briandaevermann transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT elizarbarkan transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT madelinelberkowitzcerasano transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT charlescobbs transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT franciscodiezfuertes transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT songlinding transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT jamisonmccorrison transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT nicholasjschork transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT sorayaishehata transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT kimberlyasmith transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT susanmsunkin transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT dannyntran transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT pratapvenepally transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT annamarieyanny transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT frankjsteemers transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT johnwphillips transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT amybernard transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT christofkoch transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT rogerslasken transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT richardhscheuermann transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons AT edslein transcriptomicevidencethatvoneconomoneuronsareregionallyspecializedextratelencephalicprojectingexcitatoryneurons
_version_	1718386241321304064

Transcriptomic evidence that von Economo neurons are regionally specialized extratelencephalic-projecting excitatory neurons

Ejemplares similares