Extracorporeal shock waves as curative therapy for varicose veins?

Fiorenzo Angehrn1, Christoph Kuhn1, Ortrud Sonnabend2, Axel Voss31Klinik Piano, Biel, Switzerland; 2Pathodiagnostics, Herisau, Switzerland; 3SwiTech Medical AG, Kreuzlingen, SwitzerlandAbstract: In this prospective design study the effects of low-energy partially focused extracorporeal generated sho...

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Autores principales:	Fiorenzo Angehrn, Christoph Kuhn, Ortrud Sonnabend, Axel Voss
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2008
Materias:	Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/78794d17c44947e9a3cbb57e2cf1c23f
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spelling	oai:doaj.org-article:78794d17c44947e9a3cbb57e2cf1c23f2021-12-02T03:44:33ZExtracorporeal shock waves as curative therapy for varicose veins?1178-1998https://doaj.org/article/78794d17c44947e9a3cbb57e2cf1c23f2008-03-01T00:00:00Zhttps://www.dovepress.com/extracorporeal-shock-waves-as-curative-therapy-for-varicose-veins-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Fiorenzo Angehrn1, Christoph Kuhn1, Ortrud Sonnabend2, Axel Voss31Klinik Piano, Biel, Switzerland; 2Pathodiagnostics, Herisau, Switzerland; 3SwiTech Medical AG, Kreuzlingen, SwitzerlandAbstract: In this prospective design study the effects of low-energy partially focused extracorporeal generated shock waves (ESW) onto a subcutaneous located varicose vein – left vena saphena magna (VSM) – are investigated. The treatment consisted of 4 ESW applications within 21 days. The varicose VSM of both sides were removed by surgery, and samples analyzed comparing the treated and untreated by means of histopathology. No damage to the treated varicose vein in particular and no mechanical destruction to the varicose vein’s wall could be demonstrated. However, an induction of neo-collagenogenesis was observed. The thickness of the varicose vein’s wall increased. Optimization of critical application parameters by investigating a larger number of patients may turn ESW into a non-invasive curative varicose treatment.Keywords: curative therapy, extra-cellular matrix (ECM), histopathologic changes of varicose veins, extracorporeal shock wave (ESW), progenitor cellsFiorenzo AngehrnChristoph KuhnOrtrud SonnabendAxel VossDove Medical PressarticleGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 3, Pp 175-182 (2008)
institution	DOAJ
collection	DOAJ
language	EN
topic	Geriatrics RC952-954.6
spellingShingle	Geriatrics RC952-954.6 Fiorenzo Angehrn Christoph Kuhn Ortrud Sonnabend Axel Voss Extracorporeal shock waves as curative therapy for varicose veins?
description	Fiorenzo Angehrn1, Christoph Kuhn1, Ortrud Sonnabend2, Axel Voss31Klinik Piano, Biel, Switzerland; 2Pathodiagnostics, Herisau, Switzerland; 3SwiTech Medical AG, Kreuzlingen, SwitzerlandAbstract: In this prospective design study the effects of low-energy partially focused extracorporeal generated shock waves (ESW) onto a subcutaneous located varicose vein – left vena saphena magna (VSM) – are investigated. The treatment consisted of 4 ESW applications within 21 days. The varicose VSM of both sides were removed by surgery, and samples analyzed comparing the treated and untreated by means of histopathology. No damage to the treated varicose vein in particular and no mechanical destruction to the varicose vein’s wall could be demonstrated. However, an induction of neo-collagenogenesis was observed. The thickness of the varicose vein’s wall increased. Optimization of critical application parameters by investigating a larger number of patients may turn ESW into a non-invasive curative varicose treatment.Keywords: curative therapy, extra-cellular matrix (ECM), histopathologic changes of varicose veins, extracorporeal shock wave (ESW), progenitor cells
format	article
author	Fiorenzo Angehrn Christoph Kuhn Ortrud Sonnabend Axel Voss
author_facet	Fiorenzo Angehrn Christoph Kuhn Ortrud Sonnabend Axel Voss
author_sort	Fiorenzo Angehrn
title	Extracorporeal shock waves as curative therapy for varicose veins?
title_short	Extracorporeal shock waves as curative therapy for varicose veins?
title_full	Extracorporeal shock waves as curative therapy for varicose veins?
title_fullStr	Extracorporeal shock waves as curative therapy for varicose veins?
title_full_unstemmed	Extracorporeal shock waves as curative therapy for varicose veins?
title_sort	extracorporeal shock waves as curative therapy for varicose veins?
publisher	Dove Medical Press
publishDate	2008
url	https://doaj.org/article/78794d17c44947e9a3cbb57e2cf1c23f
work_keys_str_mv	AT fiorenzoangehrn extracorporealshockwavesascurativetherapyforvaricoseveins AT christophkuhn extracorporealshockwavesascurativetherapyforvaricoseveins AT ortrudsonnabend extracorporealshockwavesascurativetherapyforvaricoseveins AT axelvoss extracorporealshockwavesascurativetherapyforvaricoseveins
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Extracorporeal shock waves as curative therapy for varicose veins?

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