Phenotype and management of chronic obstructive pulmonary disease patients in general population in China: a nationally cross-sectional study

Abstract This study aims to investigate the characteristics of the phenotype and management of chronic obstructive pulmonary disease (COPD) patients in the general population in China. We analyzed spirometry-confirmed COPD patients who were identified from a population-based, nationally representati...

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Autores principales:	Heling Bao, Guohua Jia, Shu Cong, Wanlu Sun, Jing Fan, Ning Wang, Yajing Feng, Baohua Wang, Jeffrey L. Curtis, Linhong Wang, Liwen Fang, Yahong Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Diseases of the respiratory system RC705-779
Acceso en línea:	https://doaj.org/article/787f48d6ea5f4823b721796a47500c67
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spelling	oai:doaj.org-article:787f48d6ea5f4823b721796a47500c672021-12-02T15:02:31ZPhenotype and management of chronic obstructive pulmonary disease patients in general population in China: a nationally cross-sectional study10.1038/s41533-021-00243-x2055-1010https://doaj.org/article/787f48d6ea5f4823b721796a47500c672021-06-01T00:00:00Zhttps://doi.org/10.1038/s41533-021-00243-xhttps://doaj.org/toc/2055-1010Abstract This study aims to investigate the characteristics of the phenotype and management of chronic obstructive pulmonary disease (COPD) patients in the general population in China. We analyzed spirometry-confirmed COPD patients who were identified from a population-based, nationally representative sample in China. All participants were measured with airflow limitation severity based on post-bronchodilator FEV1 percent predicted, bronchodilator responsiveness, exacerbation history, and respiratory symptoms. Among a total of 9134 COPD patients, 90.3% were non-exacerbators, 2.9% were frequent exacerbators without chronic bronchitis, 2.0% were frequent exacerbators with chronic bronchitis, and 4.8% were asthma-COPD overlap. Less than 5% of non-exacerbators ever had pulmonary function testing performed. The utilization rate of inhaled medication in non-exacerbators, exacerbators without chronic bronchitis, exacerbators with chronic bronchitis, and asthma-COPD overlap was 1.4, 23.5, 29.5, and 19.4%, respectively. A comprehensive strategy for the management of COPD patients based on phenotype in primary care is urgently needed.Heling BaoGuohua JiaShu CongWanlu SunJing FanNing WangYajing FengBaohua WangJeffrey L. CurtisLinhong WangLiwen FangYahong ChenNature PortfolioarticleDiseases of the respiratory systemRC705-779ENnpj Primary Care Respiratory Medicine, Vol 31, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the respiratory system RC705-779
spellingShingle	Diseases of the respiratory system RC705-779 Heling Bao Guohua Jia Shu Cong Wanlu Sun Jing Fan Ning Wang Yajing Feng Baohua Wang Jeffrey L. Curtis Linhong Wang Liwen Fang Yahong Chen Phenotype and management of chronic obstructive pulmonary disease patients in general population in China: a nationally cross-sectional study
description	Abstract This study aims to investigate the characteristics of the phenotype and management of chronic obstructive pulmonary disease (COPD) patients in the general population in China. We analyzed spirometry-confirmed COPD patients who were identified from a population-based, nationally representative sample in China. All participants were measured with airflow limitation severity based on post-bronchodilator FEV1 percent predicted, bronchodilator responsiveness, exacerbation history, and respiratory symptoms. Among a total of 9134 COPD patients, 90.3% were non-exacerbators, 2.9% were frequent exacerbators without chronic bronchitis, 2.0% were frequent exacerbators with chronic bronchitis, and 4.8% were asthma-COPD overlap. Less than 5% of non-exacerbators ever had pulmonary function testing performed. The utilization rate of inhaled medication in non-exacerbators, exacerbators without chronic bronchitis, exacerbators with chronic bronchitis, and asthma-COPD overlap was 1.4, 23.5, 29.5, and 19.4%, respectively. A comprehensive strategy for the management of COPD patients based on phenotype in primary care is urgently needed.
format	article
author	Heling Bao Guohua Jia Shu Cong Wanlu Sun Jing Fan Ning Wang Yajing Feng Baohua Wang Jeffrey L. Curtis Linhong Wang Liwen Fang Yahong Chen
author_facet	Heling Bao Guohua Jia Shu Cong Wanlu Sun Jing Fan Ning Wang Yajing Feng Baohua Wang Jeffrey L. Curtis Linhong Wang Liwen Fang Yahong Chen
author_sort	Heling Bao
title	Phenotype and management of chronic obstructive pulmonary disease patients in general population in China: a nationally cross-sectional study
title_short	Phenotype and management of chronic obstructive pulmonary disease patients in general population in China: a nationally cross-sectional study
title_full	Phenotype and management of chronic obstructive pulmonary disease patients in general population in China: a nationally cross-sectional study
title_fullStr	Phenotype and management of chronic obstructive pulmonary disease patients in general population in China: a nationally cross-sectional study
title_full_unstemmed	Phenotype and management of chronic obstructive pulmonary disease patients in general population in China: a nationally cross-sectional study
title_sort	phenotype and management of chronic obstructive pulmonary disease patients in general population in china: a nationally cross-sectional study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/787f48d6ea5f4823b721796a47500c67
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Phenotype and management of chronic obstructive pulmonary disease patients in general population in China: a nationally cross-sectional study

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