RNA localization is a key determinant of neurite-enriched proteome

Subcellular localization of RNAs and proteins is important for polarized cells such as neurons. Here the authors differentiate mouse embryonic stem cells into neurons, and analyze the local transcriptome, proteome, and translated transcriptome in their cell bodies and neurites, providing a unique re...

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Autores principales:	Alessandra Zappulo, David van den Bruck, Camilla Ciolli Mattioli, Vedran Franke, Koshi Imami, Erik McShane, Mireia Moreno-Estelles, Lorenzo Calviello, Andrei Filipchyk, Esteban Peguero-Sanchez, Thomas Müller, Andrew Woehler, Carmen Birchmeier, Enrique Merino, Nikolaus Rajewsky, Uwe Ohler, Esteban O. Mazzoni, Matthias Selbach, Altuna Akalin, Marina Chekulaeva
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/78855abe544f4175b8a66cdc42637e8a
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spelling	oai:doaj.org-article:78855abe544f4175b8a66cdc42637e8a2021-12-02T17:06:17ZRNA localization is a key determinant of neurite-enriched proteome10.1038/s41467-017-00690-62041-1723https://doaj.org/article/78855abe544f4175b8a66cdc42637e8a2017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00690-6https://doaj.org/toc/2041-1723Subcellular localization of RNAs and proteins is important for polarized cells such as neurons. Here the authors differentiate mouse embryonic stem cells into neurons, and analyze the local transcriptome, proteome, and translated transcriptome in their cell bodies and neurites, providing a unique resource for future studies on neuronal polarity.Alessandra ZappuloDavid van den BruckCamilla Ciolli MattioliVedran FrankeKoshi ImamiErik McShaneMireia Moreno-EstellesLorenzo CalvielloAndrei FilipchykEsteban Peguero-SanchezThomas MüllerAndrew WoehlerCarmen BirchmeierEnrique MerinoNikolaus RajewskyUwe OhlerEsteban O. MazzoniMatthias SelbachAltuna AkalinMarina ChekulaevaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Alessandra Zappulo David van den Bruck Camilla Ciolli Mattioli Vedran Franke Koshi Imami Erik McShane Mireia Moreno-Estelles Lorenzo Calviello Andrei Filipchyk Esteban Peguero-Sanchez Thomas Müller Andrew Woehler Carmen Birchmeier Enrique Merino Nikolaus Rajewsky Uwe Ohler Esteban O. Mazzoni Matthias Selbach Altuna Akalin Marina Chekulaeva RNA localization is a key determinant of neurite-enriched proteome
description	Subcellular localization of RNAs and proteins is important for polarized cells such as neurons. Here the authors differentiate mouse embryonic stem cells into neurons, and analyze the local transcriptome, proteome, and translated transcriptome in their cell bodies and neurites, providing a unique resource for future studies on neuronal polarity.
format	article
author	Alessandra Zappulo David van den Bruck Camilla Ciolli Mattioli Vedran Franke Koshi Imami Erik McShane Mireia Moreno-Estelles Lorenzo Calviello Andrei Filipchyk Esteban Peguero-Sanchez Thomas Müller Andrew Woehler Carmen Birchmeier Enrique Merino Nikolaus Rajewsky Uwe Ohler Esteban O. Mazzoni Matthias Selbach Altuna Akalin Marina Chekulaeva
author_facet	Alessandra Zappulo David van den Bruck Camilla Ciolli Mattioli Vedran Franke Koshi Imami Erik McShane Mireia Moreno-Estelles Lorenzo Calviello Andrei Filipchyk Esteban Peguero-Sanchez Thomas Müller Andrew Woehler Carmen Birchmeier Enrique Merino Nikolaus Rajewsky Uwe Ohler Esteban O. Mazzoni Matthias Selbach Altuna Akalin Marina Chekulaeva
author_sort	Alessandra Zappulo
title	RNA localization is a key determinant of neurite-enriched proteome
title_short	RNA localization is a key determinant of neurite-enriched proteome
title_full	RNA localization is a key determinant of neurite-enriched proteome
title_fullStr	RNA localization is a key determinant of neurite-enriched proteome
title_full_unstemmed	RNA localization is a key determinant of neurite-enriched proteome
title_sort	rna localization is a key determinant of neurite-enriched proteome
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/78855abe544f4175b8a66cdc42637e8a
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RNA localization is a key determinant of neurite-enriched proteome

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