Bioactive Secondary Metabolites from the Mangrove Endophytic Fungi <i>Nigrospora oryzae</i>
Mangrove forest has a distinctive habitat adapting with marine and terrestrial environment. Chemical investigation of the extract from mangrove endophytic fungi Nigrospora oryzae had resulted in the isolation of sterigmatocystin (1) and pestalopyrone (2). The structure of sterigmatocystin (1) and pe...
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Department of Chemistry, Universitas Gadjah Mada
2021
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oai:doaj.org-article:7888ab50e2054d2e911eca82c3006b7a2021-12-02T17:09:37ZBioactive Secondary Metabolites from the Mangrove Endophytic Fungi <i>Nigrospora oryzae</i>1411-94202460-157810.22146/ijc.63129https://doaj.org/article/7888ab50e2054d2e911eca82c3006b7a2021-05-01T00:00:00Zhttps://jurnal.ugm.ac.id/ijc/article/view/63129https://doaj.org/toc/1411-9420https://doaj.org/toc/2460-1578Mangrove forest has a distinctive habitat adapting with marine and terrestrial environment. Chemical investigation of the extract from mangrove endophytic fungi Nigrospora oryzae had resulted in the isolation of sterigmatocystin (1) and pestalopyrone (2). The structure of sterigmatocystin (1) and pestalopyrone (2) were elucidated using mass, UV and NMR spectrometers together with the comparison with the literature data. The study also showed that sterigmatocystin displayed moderate cytotoxicity but it could be further developed as antiviral and antibacterial agent based on the SAR information reported from its analogue and derivatives.Antonius Rolling Basa OlaTitus LapailakaHermania Em WogoJulinda Bendalina Dengga HenukAgnes SimamoraLince MukkunPeter ProkschChong Dat PhamDepartment of Chemistry, Universitas Gadjah Madaarticlenigrospora oryzaemangrovesterigmatocystinpestalopyroneChemistryQD1-999ENIndonesian Journal of Chemistry, Vol 21, Iss 4, Pp 1016-1022 (2021) |
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nigrospora oryzae mangrove sterigmatocystin pestalopyrone Chemistry QD1-999 |
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nigrospora oryzae mangrove sterigmatocystin pestalopyrone Chemistry QD1-999 Antonius Rolling Basa Ola Titus Lapailaka Hermania Em Wogo Julinda Bendalina Dengga Henuk Agnes Simamora Lince Mukkun Peter Proksch Chong Dat Pham Bioactive Secondary Metabolites from the Mangrove Endophytic Fungi <i>Nigrospora oryzae</i> |
description |
Mangrove forest has a distinctive habitat adapting with marine and terrestrial environment. Chemical investigation of the extract from mangrove endophytic fungi Nigrospora oryzae had resulted in the isolation of sterigmatocystin (1) and pestalopyrone (2). The structure of sterigmatocystin (1) and pestalopyrone (2) were elucidated using mass, UV and NMR spectrometers together with the comparison with the literature data. The study also showed that sterigmatocystin displayed moderate cytotoxicity but it could be further developed as antiviral and antibacterial agent based on the SAR information reported from its analogue and derivatives. |
format |
article |
author |
Antonius Rolling Basa Ola Titus Lapailaka Hermania Em Wogo Julinda Bendalina Dengga Henuk Agnes Simamora Lince Mukkun Peter Proksch Chong Dat Pham |
author_facet |
Antonius Rolling Basa Ola Titus Lapailaka Hermania Em Wogo Julinda Bendalina Dengga Henuk Agnes Simamora Lince Mukkun Peter Proksch Chong Dat Pham |
author_sort |
Antonius Rolling Basa Ola |
title |
Bioactive Secondary Metabolites from the Mangrove Endophytic Fungi <i>Nigrospora oryzae</i> |
title_short |
Bioactive Secondary Metabolites from the Mangrove Endophytic Fungi <i>Nigrospora oryzae</i> |
title_full |
Bioactive Secondary Metabolites from the Mangrove Endophytic Fungi <i>Nigrospora oryzae</i> |
title_fullStr |
Bioactive Secondary Metabolites from the Mangrove Endophytic Fungi <i>Nigrospora oryzae</i> |
title_full_unstemmed |
Bioactive Secondary Metabolites from the Mangrove Endophytic Fungi <i>Nigrospora oryzae</i> |
title_sort |
bioactive secondary metabolites from the mangrove endophytic fungi <i>nigrospora oryzae</i> |
publisher |
Department of Chemistry, Universitas Gadjah Mada |
publishDate |
2021 |
url |
https://doaj.org/article/7888ab50e2054d2e911eca82c3006b7a |
work_keys_str_mv |
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