Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes

Multiplexed imaging of synaptic proteins can provide useful information on the heterogeneity of synaptic architecture and plasticity. Here the authors use high affinity locked nucleic acid probes and low affinity DNA imaging probes to achieve multiplexed confocal and super-resolution imaging of syna...

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Autores principales:	Syuan-Ming Guo, Remi Veneziano, Simon Gordonov, Li Li, Eric Danielson, Karen Perez de Arce, Demian Park, Anthony B. Kulesa, Eike-Christian Wamhoff, Paul C. Blainey, Edward S. Boyden, Jeffrey R. Cottrell, Mark Bathe
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/789abbb5bbe64affabf5dc217e63e1f9
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spelling	oai:doaj.org-article:789abbb5bbe64affabf5dc217e63e1f92021-12-02T15:36:18ZMultiplexed and high-throughput neuronal fluorescence imaging with diffusible probes10.1038/s41467-019-12372-62041-1723https://doaj.org/article/789abbb5bbe64affabf5dc217e63e1f92019-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12372-6https://doaj.org/toc/2041-1723Multiplexed imaging of synaptic proteins can provide useful information on the heterogeneity of synaptic architecture and plasticity. Here the authors use high affinity locked nucleic acid probes and low affinity DNA imaging probes to achieve multiplexed confocal and super-resolution imaging of synaptic and cytoskeletal proteins.Syuan-Ming GuoRemi VenezianoSimon GordonovLi LiEric DanielsonKaren Perez de ArceDemian ParkAnthony B. KulesaEike-Christian WamhoffPaul C. BlaineyEdward S. BoydenJeffrey R. CottrellMark BatheNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Syuan-Ming Guo Remi Veneziano Simon Gordonov Li Li Eric Danielson Karen Perez de Arce Demian Park Anthony B. Kulesa Eike-Christian Wamhoff Paul C. Blainey Edward S. Boyden Jeffrey R. Cottrell Mark Bathe Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes
description	Multiplexed imaging of synaptic proteins can provide useful information on the heterogeneity of synaptic architecture and plasticity. Here the authors use high affinity locked nucleic acid probes and low affinity DNA imaging probes to achieve multiplexed confocal and super-resolution imaging of synaptic and cytoskeletal proteins.
format	article
author	Syuan-Ming Guo Remi Veneziano Simon Gordonov Li Li Eric Danielson Karen Perez de Arce Demian Park Anthony B. Kulesa Eike-Christian Wamhoff Paul C. Blainey Edward S. Boyden Jeffrey R. Cottrell Mark Bathe
author_facet	Syuan-Ming Guo Remi Veneziano Simon Gordonov Li Li Eric Danielson Karen Perez de Arce Demian Park Anthony B. Kulesa Eike-Christian Wamhoff Paul C. Blainey Edward S. Boyden Jeffrey R. Cottrell Mark Bathe
author_sort	Syuan-Ming Guo
title	Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes
title_short	Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes
title_full	Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes
title_fullStr	Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes
title_full_unstemmed	Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes
title_sort	multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/789abbb5bbe64affabf5dc217e63e1f9
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Multiplexed and high-throughput neuronal fluorescence imaging with diffusible probes

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