ASSOCIATION OF VITAMIN B12 DEFICIENCY AND METFORMIN USE IN PATIENTS PRESENTING WITH TYPE II DIABETES MELLITUS

Objective: To compare the association of vitamin B12 deficiency and metformin use in patients presenting with type II diabetes mellitus. Study Design: Case control study. Place and Duration of Study: Department of Medicine, Military Hospital Rawalpindi from Apr 2017 to Sep 2017. Methodology...

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Autores principales: Karamat Ali, Shahid Ahmed, Attia Khaliq, Aqeel Peter, Jawad Gul, Asad Habib
Formato: article
Lenguaje:EN
Publicado: Army Medical College Rawalpindi 2020
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Acceso en línea:https://doaj.org/article/789ad16baaa84485ba41816a7851f7eb
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spelling oai:doaj.org-article:789ad16baaa84485ba41816a7851f7eb2021-12-02T19:13:45ZASSOCIATION OF VITAMIN B12 DEFICIENCY AND METFORMIN USE IN PATIENTS PRESENTING WITH TYPE II DIABETES MELLITUS0030-96482411-8842https://doaj.org/article/789ad16baaa84485ba41816a7851f7eb2020-10-01T00:00:00Zhttps://pafmj.org/index.php/PAFMJ/article/view/5593https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To compare the association of vitamin B12 deficiency and metformin use in patients presenting with type II diabetes mellitus. Study Design: Case control study. Place and Duration of Study: Department of Medicine, Military Hospital Rawalpindi from Apr 2017 to Sep 2017. Methodology: All patients who fulfilled the inclusion criteria and visited OPD of department of Medicine Military Hospital Rawalpindi, were included in the study. After approval from the ethical review committee, informed written consent was taken from patients. The patients were divided into two groups group A (metformin use) & B (without metformin use). Outcome was checked by comparing both the groups for vitamin B12 deficiency. Results: Two hundred and eighty patients with diabetes mellitus were included. One hundred and seventy one (61.07%) were males and 109 (38.93%) were females, with the mean age of 59.52 ± 12.441. Vitamin B12 deficiency in group I was seen in 30 (10.71%) and in 9 patients (3.21%) in group II (OR >1). Conclusion: In conclusion, our study indicates that patients with type 2 diabetes mellitus treated with metformin should be screened for vitamin B12 deficiency, especially with longer durations of treatment.Karamat AliShahid AhmedAttia KhaliqAqeel PeterJawad GulAsad HabibArmy Medical College Rawalpindiarticlediabetes mellitustype 2metforminvitamin b12 deficiencyMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 70, Iss 5, Pp 1495-1498 (2020)
institution DOAJ
collection DOAJ
language EN
topic diabetes mellitus
type 2
metformin
vitamin b12 deficiency
Medicine
R
Medicine (General)
R5-920
spellingShingle diabetes mellitus
type 2
metformin
vitamin b12 deficiency
Medicine
R
Medicine (General)
R5-920
Karamat Ali
Shahid Ahmed
Attia Khaliq
Aqeel Peter
Jawad Gul
Asad Habib
ASSOCIATION OF VITAMIN B12 DEFICIENCY AND METFORMIN USE IN PATIENTS PRESENTING WITH TYPE II DIABETES MELLITUS
description Objective: To compare the association of vitamin B12 deficiency and metformin use in patients presenting with type II diabetes mellitus. Study Design: Case control study. Place and Duration of Study: Department of Medicine, Military Hospital Rawalpindi from Apr 2017 to Sep 2017. Methodology: All patients who fulfilled the inclusion criteria and visited OPD of department of Medicine Military Hospital Rawalpindi, were included in the study. After approval from the ethical review committee, informed written consent was taken from patients. The patients were divided into two groups group A (metformin use) & B (without metformin use). Outcome was checked by comparing both the groups for vitamin B12 deficiency. Results: Two hundred and eighty patients with diabetes mellitus were included. One hundred and seventy one (61.07%) were males and 109 (38.93%) were females, with the mean age of 59.52 ± 12.441. Vitamin B12 deficiency in group I was seen in 30 (10.71%) and in 9 patients (3.21%) in group II (OR >1). Conclusion: In conclusion, our study indicates that patients with type 2 diabetes mellitus treated with metformin should be screened for vitamin B12 deficiency, especially with longer durations of treatment.
format article
author Karamat Ali
Shahid Ahmed
Attia Khaliq
Aqeel Peter
Jawad Gul
Asad Habib
author_facet Karamat Ali
Shahid Ahmed
Attia Khaliq
Aqeel Peter
Jawad Gul
Asad Habib
author_sort Karamat Ali
title ASSOCIATION OF VITAMIN B12 DEFICIENCY AND METFORMIN USE IN PATIENTS PRESENTING WITH TYPE II DIABETES MELLITUS
title_short ASSOCIATION OF VITAMIN B12 DEFICIENCY AND METFORMIN USE IN PATIENTS PRESENTING WITH TYPE II DIABETES MELLITUS
title_full ASSOCIATION OF VITAMIN B12 DEFICIENCY AND METFORMIN USE IN PATIENTS PRESENTING WITH TYPE II DIABETES MELLITUS
title_fullStr ASSOCIATION OF VITAMIN B12 DEFICIENCY AND METFORMIN USE IN PATIENTS PRESENTING WITH TYPE II DIABETES MELLITUS
title_full_unstemmed ASSOCIATION OF VITAMIN B12 DEFICIENCY AND METFORMIN USE IN PATIENTS PRESENTING WITH TYPE II DIABETES MELLITUS
title_sort association of vitamin b12 deficiency and metformin use in patients presenting with type ii diabetes mellitus
publisher Army Medical College Rawalpindi
publishDate 2020
url https://doaj.org/article/789ad16baaa84485ba41816a7851f7eb
work_keys_str_mv AT karamatali associationofvitaminb12deficiencyandmetforminuseinpatientspresentingwithtypeiidiabetesmellitus
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AT attiakhaliq associationofvitaminb12deficiencyandmetforminuseinpatientspresentingwithtypeiidiabetesmellitus
AT aqeelpeter associationofvitaminb12deficiencyandmetforminuseinpatientspresentingwithtypeiidiabetesmellitus
AT jawadgul associationofvitaminb12deficiencyandmetforminuseinpatientspresentingwithtypeiidiabetesmellitus
AT asadhabib associationofvitaminb12deficiencyandmetforminuseinpatientspresentingwithtypeiidiabetesmellitus
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