Cardiac Tissue Engineering for the Treatment of Myocardial Infarction

Poor cell engraftment rate is one of the primary factors limiting the effectiveness of cell transfer therapy for cardiac repair. Recent studies have shown that the combination of cell-based therapy and tissue engineering technology can improve stem cell engraftment and promote the therapeutic effect...

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Autores principales:	Dongmin Yu, Xiaowei Wang, Lei Ye
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	engineered cardiac tissue myocardial infarction stem cells Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/789e67006a51439197bab40a44cbbfa8
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spelling	oai:doaj.org-article:789e67006a51439197bab40a44cbbfa82021-11-25T18:00:24ZCardiac Tissue Engineering for the Treatment of Myocardial Infarction10.3390/jcdd81101532308-3425https://doaj.org/article/789e67006a51439197bab40a44cbbfa82021-11-01T00:00:00Zhttps://www.mdpi.com/2308-3425/8/11/153https://doaj.org/toc/2308-3425Poor cell engraftment rate is one of the primary factors limiting the effectiveness of cell transfer therapy for cardiac repair. Recent studies have shown that the combination of cell-based therapy and tissue engineering technology can improve stem cell engraftment and promote the therapeutic effects of the treatment for myocardial infarction. This mini-review summarizes the recent progress in cardiac tissue engineering of cardiovascular cells from differentiated human pluripotent stem cells (PSCs), highlights their therapeutic applications for the treatment of myocardial infarction, and discusses the present challenges of cardiac tissue engineering and possible future directions from a clinical perspective.Dongmin YuXiaowei WangLei YeMDPI AGarticleengineered cardiac tissuemyocardial infarctionstem cellsDiseases of the circulatory (Cardiovascular) systemRC666-701ENJournal of Cardiovascular Development and Disease, Vol 8, Iss 153, p 153 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	engineered cardiac tissue myocardial infarction stem cells Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	engineered cardiac tissue myocardial infarction stem cells Diseases of the circulatory (Cardiovascular) system RC666-701 Dongmin Yu Xiaowei Wang Lei Ye Cardiac Tissue Engineering for the Treatment of Myocardial Infarction
description	Poor cell engraftment rate is one of the primary factors limiting the effectiveness of cell transfer therapy for cardiac repair. Recent studies have shown that the combination of cell-based therapy and tissue engineering technology can improve stem cell engraftment and promote the therapeutic effects of the treatment for myocardial infarction. This mini-review summarizes the recent progress in cardiac tissue engineering of cardiovascular cells from differentiated human pluripotent stem cells (PSCs), highlights their therapeutic applications for the treatment of myocardial infarction, and discusses the present challenges of cardiac tissue engineering and possible future directions from a clinical perspective.
format	article
author	Dongmin Yu Xiaowei Wang Lei Ye
author_facet	Dongmin Yu Xiaowei Wang Lei Ye
author_sort	Dongmin Yu
title	Cardiac Tissue Engineering for the Treatment of Myocardial Infarction
title_short	Cardiac Tissue Engineering for the Treatment of Myocardial Infarction
title_full	Cardiac Tissue Engineering for the Treatment of Myocardial Infarction
title_fullStr	Cardiac Tissue Engineering for the Treatment of Myocardial Infarction
title_full_unstemmed	Cardiac Tissue Engineering for the Treatment of Myocardial Infarction
title_sort	cardiac tissue engineering for the treatment of myocardial infarction
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/789e67006a51439197bab40a44cbbfa8
work_keys_str_mv	AT dongminyu cardiactissueengineeringforthetreatmentofmyocardialinfarction AT xiaoweiwang cardiactissueengineeringforthetreatmentofmyocardialinfarction AT leiye cardiactissueengineeringforthetreatmentofmyocardialinfarction
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Cardiac Tissue Engineering for the Treatment of Myocardial Infarction

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