Effect of Acupuncture on Pregnancy-Related Insomnia and Melatonin: A Single-Blinded, Randomized, Placebo-Controlled Trial

Saeedeh Foroughinia,1 Kamran Hessami,2,3 Nasrin Asadi,3 Leila Foroughinia,4 Mohammadjavad Hadianfard,5 Azadeh Hajihosseini,5 Najmeh Pirasteh,5 Mehrdad Vossoughi,6 Homeira Vafaei,3 Azam Faraji,3 Maryam Kasraeian,3 Mehrnoosh Doroudchi,7 Mohammad Rafiee Monjezi,8 Shohreh Roozmeh,3 Khadije Bazrafshan3 1...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Foroughinia S, Hessami K, Asadi N, Foroughinia L, Hadianfard M, Hajihosseini A, Pirasteh N, Vossoughi M, Vafaei H, Faraji A, Kasraeian M, Doroudchi M, Rafiee Monjezi M, Roozmeh S, Bazrafshan K
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	acupuncture pregnancy insomnia melatonin Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495
Acceso en línea:	https://doaj.org/article/78aa8dcd25c84b1da02fce714eba0dd0
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:78aa8dcd25c84b1da02fce714eba0dd0
record_format	dspace
spelling	oai:doaj.org-article:78aa8dcd25c84b1da02fce714eba0dd02021-12-02T09:24:45ZEffect of Acupuncture on Pregnancy-Related Insomnia and Melatonin: A Single-Blinded, Randomized, Placebo-Controlled Trial1179-1608https://doaj.org/article/78aa8dcd25c84b1da02fce714eba0dd02020-05-01T00:00:00Zhttps://www.dovepress.com/effect-of-acupuncture-on-pregnancy-related-insomnia-and-melatonin-a-si-peer-reviewed-article-NSShttps://doaj.org/toc/1179-1608Saeedeh Foroughinia,1 Kamran Hessami,2,3 Nasrin Asadi,3 Leila Foroughinia,4 Mohammadjavad Hadianfard,5 Azadeh Hajihosseini,5 Najmeh Pirasteh,5 Mehrdad Vossoughi,6 Homeira Vafaei,3 Azam Faraji,3 Maryam Kasraeian,3 Mehrnoosh Doroudchi,7 Mohammad Rafiee Monjezi,8 Shohreh Roozmeh,3 Khadije Bazrafshan3 1Obstetrics and Gynecology Department, Shiraz University of Medical Sciences, Shiraz, Iran; 2Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran; 3Maternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; 4Box Hill Hospital, FRANZCOG, Eastern Health, Victoria, Australia; 5Physical Medicine and Rehabilitation Department, Shiraz University of Medical Sciences, Shiraz, Iran; 6Oral and Dental Disease Research Center, Department of Dental Public Health, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran; 7Department of Immunology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran; 8Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, IranCorrespondence: Nasrin AsadiMaternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, IranTel +98-71-36128257Fax +98-71-362128257Email nasadi2012@yahoo.caObjective: The aim of the current study is to evaluate the efficacy and safety of acupuncture on sleep quality and overnight melatonin secretion, measured as urinary 6-sulfatoxymelatonin, in pregnant women.Patients and Methods: This randomized, parallel, single-blinded (participant), controlled trial was conducted on 72 pregnant women with insomnia. Study participants were randomly assigned to either the intervention, 10 sessions of acupuncture treatment over a 3-week period, or control group by block randomization (1:1). Patients in both groups were evaluated at baseline and post-treatment (third week) using the Pittsburgh Sleep Quality Index (PSQI) score (as the primary outcome) and urinary 6-sulfatoxymelatonin.Results: Fifty-five of 72 participants completed the study. There was no statistically significant difference regarding PSQI score and 6-sulfatoxymelatonin level between intervention and control groups at the baseline (P=0.169 and P=0.496). At the end of the study period, treatment with acupuncture significantly improved the PSQI score (P< 0.001) with a large effect size of 3.7, as well as 6-sulfatoxymelatonin level (P=0.020) with a medium effect size of 0.6 as compared to the control group. No adverse effects were noted during acupuncture sessions and follow-up visits.Conclusion: Acupuncture was shown to significantly improve the sleep quality in pregnant women, possibly through increasing melatonin secretion, and could be recommended as a low-cost and low-risk alternative treatment to pharmacological therapies.Keywords: acupuncture, pregnancy, insomnia, melatoninForoughinia SHessami KAsadi NForoughinia LHadianfard MHajihosseini APirasteh NVossoughi MVafaei HFaraji AKasraeian MDoroudchi MRafiee Monjezi MRoozmeh SBazrafshan KDove Medical PressarticleacupuncturepregnancyinsomniamelatoninPsychiatryRC435-571Neurophysiology and neuropsychologyQP351-495ENNature and Science of Sleep, Vol Volume 12, Pp 271-278 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	acupuncture pregnancy insomnia melatonin Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495
spellingShingle	acupuncture pregnancy insomnia melatonin Psychiatry RC435-571 Neurophysiology and neuropsychology QP351-495 Foroughinia S Hessami K Asadi N Foroughinia L Hadianfard M Hajihosseini A Pirasteh N Vossoughi M Vafaei H Faraji A Kasraeian M Doroudchi M Rafiee Monjezi M Roozmeh S Bazrafshan K Effect of Acupuncture on Pregnancy-Related Insomnia and Melatonin: A Single-Blinded, Randomized, Placebo-Controlled Trial
description	Saeedeh Foroughinia,1 Kamran Hessami,2,3 Nasrin Asadi,3 Leila Foroughinia,4 Mohammadjavad Hadianfard,5 Azadeh Hajihosseini,5 Najmeh Pirasteh,5 Mehrdad Vossoughi,6 Homeira Vafaei,3 Azam Faraji,3 Maryam Kasraeian,3 Mehrnoosh Doroudchi,7 Mohammad Rafiee Monjezi,8 Shohreh Roozmeh,3 Khadije Bazrafshan3 1Obstetrics and Gynecology Department, Shiraz University of Medical Sciences, Shiraz, Iran; 2Student Research Committee, Shiraz University of Medical Sciences, Shiraz, Iran; 3Maternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; 4Box Hill Hospital, FRANZCOG, Eastern Health, Victoria, Australia; 5Physical Medicine and Rehabilitation Department, Shiraz University of Medical Sciences, Shiraz, Iran; 6Oral and Dental Disease Research Center, Department of Dental Public Health, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran; 7Department of Immunology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran; 8Shiraz Institute for Cancer Research, Shiraz University of Medical Sciences, Shiraz, IranCorrespondence: Nasrin AsadiMaternal-Fetal Medicine Research Center, Shiraz University of Medical Sciences, Shiraz, IranTel +98-71-36128257Fax +98-71-362128257Email nasadi2012@yahoo.caObjective: The aim of the current study is to evaluate the efficacy and safety of acupuncture on sleep quality and overnight melatonin secretion, measured as urinary 6-sulfatoxymelatonin, in pregnant women.Patients and Methods: This randomized, parallel, single-blinded (participant), controlled trial was conducted on 72 pregnant women with insomnia. Study participants were randomly assigned to either the intervention, 10 sessions of acupuncture treatment over a 3-week period, or control group by block randomization (1:1). Patients in both groups were evaluated at baseline and post-treatment (third week) using the Pittsburgh Sleep Quality Index (PSQI) score (as the primary outcome) and urinary 6-sulfatoxymelatonin.Results: Fifty-five of 72 participants completed the study. There was no statistically significant difference regarding PSQI score and 6-sulfatoxymelatonin level between intervention and control groups at the baseline (P=0.169 and P=0.496). At the end of the study period, treatment with acupuncture significantly improved the PSQI score (P< 0.001) with a large effect size of 3.7, as well as 6-sulfatoxymelatonin level (P=0.020) with a medium effect size of 0.6 as compared to the control group. No adverse effects were noted during acupuncture sessions and follow-up visits.Conclusion: Acupuncture was shown to significantly improve the sleep quality in pregnant women, possibly through increasing melatonin secretion, and could be recommended as a low-cost and low-risk alternative treatment to pharmacological therapies.Keywords: acupuncture, pregnancy, insomnia, melatonin
format	article
author	Foroughinia S Hessami K Asadi N Foroughinia L Hadianfard M Hajihosseini A Pirasteh N Vossoughi M Vafaei H Faraji A Kasraeian M Doroudchi M Rafiee Monjezi M Roozmeh S Bazrafshan K
author_facet	Foroughinia S Hessami K Asadi N Foroughinia L Hadianfard M Hajihosseini A Pirasteh N Vossoughi M Vafaei H Faraji A Kasraeian M Doroudchi M Rafiee Monjezi M Roozmeh S Bazrafshan K
author_sort	Foroughinia S
title	Effect of Acupuncture on Pregnancy-Related Insomnia and Melatonin: A Single-Blinded, Randomized, Placebo-Controlled Trial
title_short	Effect of Acupuncture on Pregnancy-Related Insomnia and Melatonin: A Single-Blinded, Randomized, Placebo-Controlled Trial
title_full	Effect of Acupuncture on Pregnancy-Related Insomnia and Melatonin: A Single-Blinded, Randomized, Placebo-Controlled Trial
title_fullStr	Effect of Acupuncture on Pregnancy-Related Insomnia and Melatonin: A Single-Blinded, Randomized, Placebo-Controlled Trial
title_full_unstemmed	Effect of Acupuncture on Pregnancy-Related Insomnia and Melatonin: A Single-Blinded, Randomized, Placebo-Controlled Trial
title_sort	effect of acupuncture on pregnancy-related insomnia and melatonin: a single-blinded, randomized, placebo-controlled trial
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/78aa8dcd25c84b1da02fce714eba0dd0
work_keys_str_mv	AT foroughinias effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT hessamik effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT asadin effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT foroughinial effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT hadianfardm effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT hajihosseinia effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT pirastehn effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT vossoughim effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT vafaeih effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT farajia effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT kasraeianm effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT doroudchim effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT rafieemonjezim effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT roozmehs effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial AT bazrafshank effectofacupunctureonpregnancyrelatedinsomniaandmelatoninasingleblindedrandomizedplacebocontrolledtrial
_version_	1718398130027757568

Effect of Acupuncture on Pregnancy-Related Insomnia and Melatonin: A Single-Blinded, Randomized, Placebo-Controlled Trial

Ejemplares similares