Complete sequencing and pan-genomic analysis of Lactobacillus delbrueckii subsp. bulgaricus reveal its genetic basis for industrial yogurt production.

Lactobacillus delbrueckii subsp. bulgaricus (Lb. bulgaricus) is an important species of Lactic Acid Bacteria (LAB) used for cheese and yogurt fermentation. The genome of Lb. bulgaricus 2038, an industrial strain mainly used for yogurt production, was completely sequenced and compared against the oth...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Pei Hao, Huajun Zheng, Yao Yu, Guohui Ding, Wenyi Gu, Shuting Chen, Zhonghao Yu, Shuangxi Ren, Munehiro Oda, Tomonobu Konno, Shengyue Wang, Xuan Li, Zai-Si Ji, Guoping Zhao
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2011
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/78af496c1c2a4d109f9e84d6650334e1
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:78af496c1c2a4d109f9e84d6650334e1
record_format	dspace
spelling	oai:doaj.org-article:78af496c1c2a4d109f9e84d6650334e12021-11-18T07:00:24ZComplete sequencing and pan-genomic analysis of Lactobacillus delbrueckii subsp. bulgaricus reveal its genetic basis for industrial yogurt production.1932-620310.1371/journal.pone.0015964https://doaj.org/article/78af496c1c2a4d109f9e84d6650334e12011-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21264216/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203Lactobacillus delbrueckii subsp. bulgaricus (Lb. bulgaricus) is an important species of Lactic Acid Bacteria (LAB) used for cheese and yogurt fermentation. The genome of Lb. bulgaricus 2038, an industrial strain mainly used for yogurt production, was completely sequenced and compared against the other two ATCC collection strains of the same subspecies. Specific physiological properties of strain 2038, such as lysine biosynthesis, formate production, aspartate-related carbon-skeleton intermediate metabolism, unique EPS synthesis and efficient DNA restriction/modification systems, are all different from those of the collection strains that might benefit the industrial production of yogurt. Other common features shared by Lb. bulgaricus strains, such as efficient protocooperation with Streptococcus thermophilus and lactate production as well as well-equipped stress tolerance mechanisms may account for it being selected originally for yogurt fermentation industry. Multiple lines of evidence suggested that Lb. bulgaricus 2038 was genetically closer to the common ancestor of the subspecies than the other two sequenced collection strains, probably due to a strict industrial maintenance process for strain 2038 that might have halted its genome decay and sustained a gene network suitable for large scale yogurt production.Pei HaoHuajun ZhengYao YuGuohui DingWenyi GuShuting ChenZhonghao YuShuangxi RenMunehiro OdaTomonobu KonnoShengyue WangXuan LiZai-Si JiGuoping ZhaoPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 6, Iss 1, p e15964 (2011)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Pei Hao Huajun Zheng Yao Yu Guohui Ding Wenyi Gu Shuting Chen Zhonghao Yu Shuangxi Ren Munehiro Oda Tomonobu Konno Shengyue Wang Xuan Li Zai-Si Ji Guoping Zhao Complete sequencing and pan-genomic analysis of Lactobacillus delbrueckii subsp. bulgaricus reveal its genetic basis for industrial yogurt production.
description	Lactobacillus delbrueckii subsp. bulgaricus (Lb. bulgaricus) is an important species of Lactic Acid Bacteria (LAB) used for cheese and yogurt fermentation. The genome of Lb. bulgaricus 2038, an industrial strain mainly used for yogurt production, was completely sequenced and compared against the other two ATCC collection strains of the same subspecies. Specific physiological properties of strain 2038, such as lysine biosynthesis, formate production, aspartate-related carbon-skeleton intermediate metabolism, unique EPS synthesis and efficient DNA restriction/modification systems, are all different from those of the collection strains that might benefit the industrial production of yogurt. Other common features shared by Lb. bulgaricus strains, such as efficient protocooperation with Streptococcus thermophilus and lactate production as well as well-equipped stress tolerance mechanisms may account for it being selected originally for yogurt fermentation industry. Multiple lines of evidence suggested that Lb. bulgaricus 2038 was genetically closer to the common ancestor of the subspecies than the other two sequenced collection strains, probably due to a strict industrial maintenance process for strain 2038 that might have halted its genome decay and sustained a gene network suitable for large scale yogurt production.
format	article
author	Pei Hao Huajun Zheng Yao Yu Guohui Ding Wenyi Gu Shuting Chen Zhonghao Yu Shuangxi Ren Munehiro Oda Tomonobu Konno Shengyue Wang Xuan Li Zai-Si Ji Guoping Zhao
author_facet	Pei Hao Huajun Zheng Yao Yu Guohui Ding Wenyi Gu Shuting Chen Zhonghao Yu Shuangxi Ren Munehiro Oda Tomonobu Konno Shengyue Wang Xuan Li Zai-Si Ji Guoping Zhao
author_sort	Pei Hao
title	Complete sequencing and pan-genomic analysis of Lactobacillus delbrueckii subsp. bulgaricus reveal its genetic basis for industrial yogurt production.
title_short	Complete sequencing and pan-genomic analysis of Lactobacillus delbrueckii subsp. bulgaricus reveal its genetic basis for industrial yogurt production.
title_full	Complete sequencing and pan-genomic analysis of Lactobacillus delbrueckii subsp. bulgaricus reveal its genetic basis for industrial yogurt production.
title_fullStr	Complete sequencing and pan-genomic analysis of Lactobacillus delbrueckii subsp. bulgaricus reveal its genetic basis for industrial yogurt production.
title_full_unstemmed	Complete sequencing and pan-genomic analysis of Lactobacillus delbrueckii subsp. bulgaricus reveal its genetic basis for industrial yogurt production.
title_sort	complete sequencing and pan-genomic analysis of lactobacillus delbrueckii subsp. bulgaricus reveal its genetic basis for industrial yogurt production.
publisher	Public Library of Science (PLoS)
publishDate	2011
url	https://doaj.org/article/78af496c1c2a4d109f9e84d6650334e1
work_keys_str_mv	AT peihao completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction AT huajunzheng completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction AT yaoyu completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction AT guohuiding completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction AT wenyigu completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction AT shutingchen completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction AT zhonghaoyu completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction AT shuangxiren completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction AT munehirooda completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction AT tomonobukonno completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction AT shengyuewang completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction AT xuanli completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction AT zaisiji completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction AT guopingzhao completesequencingandpangenomicanalysisoflactobacillusdelbrueckiisubspbulgaricusrevealitsgeneticbasisforindustrialyogurtproduction
_version_	1718424049455988736

Complete sequencing and pan-genomic analysis of Lactobacillus delbrueckii subsp. bulgaricus reveal its genetic basis for industrial yogurt production.

Ejemplares similares