MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION

Abstract. Common polymorphisms of interleukin-1β, receptor antagonist interleukin-1, and interleukin-4 genes have been studied among the patients with rheumatoid arthritis of Bashkir origin, living in Chelyabinsk Region. As a result of study, an increased frequency of interleukin-1β homozygosity for...

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Autores principales: A. L. Burmistrova, D. S. Stashkevich, T. A. Susslova, I. V. Devald, A. O. Issakanova, O. N. Dimcheva
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Publicado: SPb RAACI 2014
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spelling oai:doaj.org-article:78b5fc0e5fe0430793684400aae8d1a32021-11-18T08:03:39ZMOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION1563-06252313-741X10.15789/1563-0625-2007-6-631-634https://doaj.org/article/78b5fc0e5fe0430793684400aae8d1a32014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/253https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Common polymorphisms of interleukin-1β, receptor antagonist interleukin-1, and interleukin-4 genes have been studied among the patients with rheumatoid arthritis of Bashkir origin, living in Chelyabinsk Region. As a result of study, an increased frequency of interleukin-1β homozygosity for a high-producer allele was found. An association has been revealed between the homozygosity for 2-repeat allele of interleukin-4, and the age of disease onset.A. L. BurmistrovaD. S. StashkevichT. A. SusslovaI. V. DevaldA. O. IssakanovaO. N. DimchevaSPb RAACIarticlegene polymorphismcytokinesrheumatoid arthritisImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 9, Iss 6, Pp 631-634 (2014)
institution DOAJ
collection DOAJ
language RU
topic gene polymorphism
cytokines
rheumatoid arthritis
Immunologic diseases. Allergy
RC581-607
spellingShingle gene polymorphism
cytokines
rheumatoid arthritis
Immunologic diseases. Allergy
RC581-607
A. L. Burmistrova
D. S. Stashkevich
T. A. Susslova
I. V. Devald
A. O. Issakanova
O. N. Dimcheva
MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION
description Abstract. Common polymorphisms of interleukin-1β, receptor antagonist interleukin-1, and interleukin-4 genes have been studied among the patients with rheumatoid arthritis of Bashkir origin, living in Chelyabinsk Region. As a result of study, an increased frequency of interleukin-1β homozygosity for a high-producer allele was found. An association has been revealed between the homozygosity for 2-repeat allele of interleukin-4, and the age of disease onset.
format article
author A. L. Burmistrova
D. S. Stashkevich
T. A. Susslova
I. V. Devald
A. O. Issakanova
O. N. Dimcheva
author_facet A. L. Burmistrova
D. S. Stashkevich
T. A. Susslova
I. V. Devald
A. O. Issakanova
O. N. Dimcheva
author_sort A. L. Burmistrova
title MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION
title_short MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION
title_full MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION
title_fullStr MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION
title_full_unstemmed MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION
title_sort molecular biology analysis of il -1β, il -4, and il -1β ra gene polymorphisms in ethnic bashkir patients with rheumatoid arthritis, living in c helyabinsk region
publisher SPb RAACI
publishDate 2014
url https://doaj.org/article/78b5fc0e5fe0430793684400aae8d1a3
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