MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION
Abstract. Common polymorphisms of interleukin-1β, receptor antagonist interleukin-1, and interleukin-4 genes have been studied among the patients with rheumatoid arthritis of Bashkir origin, living in Chelyabinsk Region. As a result of study, an increased frequency of interleukin-1β homozygosity for...
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oai:doaj.org-article:78b5fc0e5fe0430793684400aae8d1a32021-11-18T08:03:39ZMOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION1563-06252313-741X10.15789/1563-0625-2007-6-631-634https://doaj.org/article/78b5fc0e5fe0430793684400aae8d1a32014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/253https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Common polymorphisms of interleukin-1β, receptor antagonist interleukin-1, and interleukin-4 genes have been studied among the patients with rheumatoid arthritis of Bashkir origin, living in Chelyabinsk Region. As a result of study, an increased frequency of interleukin-1β homozygosity for a high-producer allele was found. An association has been revealed between the homozygosity for 2-repeat allele of interleukin-4, and the age of disease onset.A. L. BurmistrovaD. S. StashkevichT. A. SusslovaI. V. DevaldA. O. IssakanovaO. N. DimchevaSPb RAACIarticlegene polymorphismcytokinesrheumatoid arthritisImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 9, Iss 6, Pp 631-634 (2014) |
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DOAJ |
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gene polymorphism cytokines rheumatoid arthritis Immunologic diseases. Allergy RC581-607 |
spellingShingle |
gene polymorphism cytokines rheumatoid arthritis Immunologic diseases. Allergy RC581-607 A. L. Burmistrova D. S. Stashkevich T. A. Susslova I. V. Devald A. O. Issakanova O. N. Dimcheva MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION |
description |
Abstract. Common polymorphisms of interleukin-1β, receptor antagonist interleukin-1, and interleukin-4 genes have been studied among the patients with rheumatoid arthritis of Bashkir origin, living in Chelyabinsk Region. As a result of study, an increased frequency of interleukin-1β homozygosity for a high-producer allele was found. An association has been revealed between the homozygosity for 2-repeat allele of interleukin-4, and the age of disease onset. |
format |
article |
author |
A. L. Burmistrova D. S. Stashkevich T. A. Susslova I. V. Devald A. O. Issakanova O. N. Dimcheva |
author_facet |
A. L. Burmistrova D. S. Stashkevich T. A. Susslova I. V. Devald A. O. Issakanova O. N. Dimcheva |
author_sort |
A. L. Burmistrova |
title |
MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION |
title_short |
MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION |
title_full |
MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION |
title_fullStr |
MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION |
title_full_unstemmed |
MOLECULAR BIOLOGY ANALYSIS OF IL -1Β, IL -4, AND IL -1Β RA GENE POLYMORPHISMS IN ETHNIC BASHKIR PATIENTS WITH RHEUMATOID ARTHRITIS, LIVING IN C HELYABINSK REGION |
title_sort |
molecular biology analysis of il -1β, il -4, and il -1β ra gene polymorphisms in ethnic bashkir patients with rheumatoid arthritis, living in c helyabinsk region |
publisher |
SPb RAACI |
publishDate |
2014 |
url |
https://doaj.org/article/78b5fc0e5fe0430793684400aae8d1a3 |
work_keys_str_mv |
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1718422552966070272 |