Interleukin 10 mutant zebrafish have an enhanced interferon gamma response and improved survival against a Mycobacterium marinum infection
Abstract Tuberculosis ranks as one of the world’s deadliest infectious diseases causing more than a million casualties annually. IL10 inhibits the function of Th1 type cells, and IL10 deficiency has been associated with an improved resistance against Mycobacterium tuberculosis infection in a mouse m...
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Main Authors: | Sanna-Kaisa E. Harjula, Markus J. T. Ojanen, Sinja Taavitsainen, Matti Nykter, Mika Rämet |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2018
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Online Access: | https://doaj.org/article/78c1723443f04eeab0de7d9debe41c41 |
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