Local Application of Antibiotics in Periodontal Pockets
Given the fact that, periodontal disease is a disease with an infective agent, treatment by using antibiotics with scaling and root planing (SRP) has been considered as an adjunctive therapy. According to disadvantages of systemic antibiotic therapy such as: resistance, fluctuations in concentration...
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Babol University of Medical Sciences
2011
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oai:doaj.org-article:78cbca07d0b74763b0e6647db2287b722021-11-10T08:56:19ZLocal Application of Antibiotics in Periodontal Pockets1561-41072251-7170https://doaj.org/article/78cbca07d0b74763b0e6647db2287b722011-02-01T00:00:00Zhttp://jbums.org/article-1-3724-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Given the fact that, periodontal disease is a disease with an infective agent, treatment by using antibiotics with scaling and root planing (SRP) has been considered as an adjunctive therapy. According to disadvantages of systemic antibiotic therapy such as: resistance, fluctuations in concentration, need for cooperation and side effects, local drug delivery systems in the form of irrigants or forms of drug releasing agents, seems to be a suitable substitute. Because periodontal diseases are often limited to several teeth. A local delivery device consists of a drug reservoir and a limiting element that controls the rate of medicament release. The goal is to maintain effective concentrations of chemotherapeutic agents at the site of action for long periods, despite drug loss from cervicular fluid clearance. Current data suggest that local delivery of antimicrobials into a periodontal pocket can improve periodontal health. It can be concluded that the adjunctive use of local drug delivery may provide a defined, but limited, beneficial response.B AmoianAA MoghadamniaB VadiatiJ MehraniBabol University of Medical Sciencesarticlechronic periodontitislocal drug delivery systemsantibioticantisepticMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 13, Iss 1, Pp 82-89 (2011) |
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chronic periodontitis local drug delivery systems antibiotic antiseptic Medicine R Medicine (General) R5-920 |
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chronic periodontitis local drug delivery systems antibiotic antiseptic Medicine R Medicine (General) R5-920 B Amoian AA Moghadamnia B Vadiati J Mehrani Local Application of Antibiotics in Periodontal Pockets |
description |
Given the fact that, periodontal disease is a disease with an infective agent, treatment by using antibiotics with scaling and root planing (SRP) has been considered as an adjunctive therapy. According to disadvantages of systemic antibiotic therapy such as: resistance, fluctuations in concentration, need for cooperation and side effects, local drug delivery systems in the form of irrigants or forms of drug releasing agents, seems to be a suitable substitute. Because periodontal diseases are often limited to several teeth. A local delivery device consists of a drug reservoir and a limiting element that controls the rate of medicament release. The goal is to maintain effective concentrations of chemotherapeutic agents at the site of action for long periods, despite drug loss from cervicular fluid clearance. Current data suggest that local delivery of antimicrobials into a periodontal pocket can improve periodontal health. It can be concluded that the adjunctive use of local drug delivery may provide a defined, but limited, beneficial response. |
format |
article |
author |
B Amoian AA Moghadamnia B Vadiati J Mehrani |
author_facet |
B Amoian AA Moghadamnia B Vadiati J Mehrani |
author_sort |
B Amoian |
title |
Local Application of Antibiotics in Periodontal Pockets |
title_short |
Local Application of Antibiotics in Periodontal Pockets |
title_full |
Local Application of Antibiotics in Periodontal Pockets |
title_fullStr |
Local Application of Antibiotics in Periodontal Pockets |
title_full_unstemmed |
Local Application of Antibiotics in Periodontal Pockets |
title_sort |
local application of antibiotics in periodontal pockets |
publisher |
Babol University of Medical Sciences |
publishDate |
2011 |
url |
https://doaj.org/article/78cbca07d0b74763b0e6647db2287b72 |
work_keys_str_mv |
AT bamoian localapplicationofantibioticsinperiodontalpockets AT aamoghadamnia localapplicationofantibioticsinperiodontalpockets AT bvadiati localapplicationofantibioticsinperiodontalpockets AT jmehrani localapplicationofantibioticsinperiodontalpockets |
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1718440298970873856 |