Local Application of Antibiotics in Periodontal Pockets

Given the fact that, periodontal disease is a disease with an infective agent, treatment by using antibiotics with scaling and root planing (SRP) has been considered as an adjunctive therapy. According to disadvantages of systemic antibiotic therapy such as: resistance, fluctuations in concentration...

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Autores principales: B Amoian, AA Moghadamnia, B Vadiati, J Mehrani
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Publicado: Babol University of Medical Sciences 2011
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Acceso en línea:https://doaj.org/article/78cbca07d0b74763b0e6647db2287b72
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spelling oai:doaj.org-article:78cbca07d0b74763b0e6647db2287b722021-11-10T08:56:19ZLocal Application of Antibiotics in Periodontal Pockets1561-41072251-7170https://doaj.org/article/78cbca07d0b74763b0e6647db2287b722011-02-01T00:00:00Zhttp://jbums.org/article-1-3724-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Given the fact that, periodontal disease is a disease with an infective agent, treatment by using antibiotics with scaling and root planing (SRP) has been considered as an adjunctive therapy. According to disadvantages of systemic antibiotic therapy such as: resistance, fluctuations in concentration, need for cooperation and side effects, local drug delivery systems in the form of irrigants or forms of drug releasing agents, seems to be a suitable substitute. Because periodontal diseases are often limited to several teeth. A local delivery device consists of a drug reservoir and a limiting element that controls the rate of medicament release. The goal is to maintain effective concentrations of chemotherapeutic agents at the site of action for long periods, despite drug loss from cervicular fluid clearance. Current data suggest that local delivery of antimicrobials into a periodontal pocket can improve periodontal health. It can be concluded that the adjunctive use of local drug delivery may provide a defined, but limited, beneficial response.B AmoianAA MoghadamniaB VadiatiJ MehraniBabol University of Medical Sciencesarticlechronic periodontitislocal drug delivery systemsantibioticantisepticMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 13, Iss 1, Pp 82-89 (2011)
institution DOAJ
collection DOAJ
language EN
FA
topic chronic periodontitis
local drug delivery systems
antibiotic
antiseptic
Medicine
R
Medicine (General)
R5-920
spellingShingle chronic periodontitis
local drug delivery systems
antibiotic
antiseptic
Medicine
R
Medicine (General)
R5-920
B Amoian
AA Moghadamnia
B Vadiati
J Mehrani
Local Application of Antibiotics in Periodontal Pockets
description Given the fact that, periodontal disease is a disease with an infective agent, treatment by using antibiotics with scaling and root planing (SRP) has been considered as an adjunctive therapy. According to disadvantages of systemic antibiotic therapy such as: resistance, fluctuations in concentration, need for cooperation and side effects, local drug delivery systems in the form of irrigants or forms of drug releasing agents, seems to be a suitable substitute. Because periodontal diseases are often limited to several teeth. A local delivery device consists of a drug reservoir and a limiting element that controls the rate of medicament release. The goal is to maintain effective concentrations of chemotherapeutic agents at the site of action for long periods, despite drug loss from cervicular fluid clearance. Current data suggest that local delivery of antimicrobials into a periodontal pocket can improve periodontal health. It can be concluded that the adjunctive use of local drug delivery may provide a defined, but limited, beneficial response.
format article
author B Amoian
AA Moghadamnia
B Vadiati
J Mehrani
author_facet B Amoian
AA Moghadamnia
B Vadiati
J Mehrani
author_sort B Amoian
title Local Application of Antibiotics in Periodontal Pockets
title_short Local Application of Antibiotics in Periodontal Pockets
title_full Local Application of Antibiotics in Periodontal Pockets
title_fullStr Local Application of Antibiotics in Periodontal Pockets
title_full_unstemmed Local Application of Antibiotics in Periodontal Pockets
title_sort local application of antibiotics in periodontal pockets
publisher Babol University of Medical Sciences
publishDate 2011
url https://doaj.org/article/78cbca07d0b74763b0e6647db2287b72
work_keys_str_mv AT bamoian localapplicationofantibioticsinperiodontalpockets
AT aamoghadamnia localapplicationofantibioticsinperiodontalpockets
AT bvadiati localapplicationofantibioticsinperiodontalpockets
AT jmehrani localapplicationofantibioticsinperiodontalpockets
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