Phased differentiation of γδ T and T CD8 tumor-infiltrating lymphocytes revealed by single-cell transcriptomics of human cancers
γδ T lymphocytes diverge from conventional T CD8 lymphocytes for ontogeny, homing, and antigen specificity, but whether their differentiation in tumors also deviates was unknown. Using innovative analyses of our original and ~150 published single-cell RNA sequencing datasets validated by phenotyping...
Guardado en:
Autores principales: | Juan-Pablo Cerapio, Marion Perrier, Camille-Charlotte Balança, Pauline Gravelle, Fréderic Pont, Christel Devaud, Don-Marc Franchini, Virginie Féliu, Marie Tosolini, Carine Valle, Fréderic Lopez, Anne Quillet-Mary, Loic Ysebaert, Alejandra Martinez, Jean Pierre Delord, Maha Ayyoub, Camille Laurent, Jean-Jacques Fournie |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Taylor & Francis Group
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/78cd3c370634474b9f9993cdc250af9f |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Single-Cell RNAseq Profiling of Human γδ T Lymphocytes in Virus-Related Cancers and COVID-19 Disease
por: Juan Pablo Cerapio, et al.
Publicado: (2021) -
Intramuscular Vaccination With the HSV-1(VC2) Live-Attenuated Vaccine Strain Confers Protection Against Viral Ocular Immunopathogenesis Associated With γδT Cell Intracorneal Infiltration
por: Rafiq Nabi, et al.
Publicado: (2021) -
Fatty acid desaturase 1 knockout mice are lean with improved glycemic control and decreased development of atheromatous plaque
por: Powell DR, et al.
Publicado: (2016) -
Do greenhouse experiments predict willow responses to long term flooding events in the field?
por: Cerrillo,Teresa, et al.
Publicado: (2013) -
Quaternary lacustrine braid deltas on Lake General Carrera in southern Chile
por: Bell,C. Mike
Publicado: (2009)