Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation

Cellular overgrowth and fibrosis in the foreign body response can compromise the function of transplanted cells. Here, the authors report on the zwitterionically modified alginates for the encapsulation of cells to reduce cellular overgrowth and demonstrate application in mice, dogs and pigs.

Guardado en:
Detalles Bibliográficos
Autores principales: Qingsheng Liu, Alan Chiu, Long-Hai Wang, Duo An, Monica Zhong, Alexandra M. Smink, Bart J. de Haan, Paul de Vos, Kevin Keane, Andreas Vegge, Esther Y. Chen, Wei Song, Wendy F. Liu, James Flanders, Claude Rescan, Lars Groth Grunnet, Xi Wang, Minglin Ma
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Q
Acceso en línea:https://doaj.org/article/78e679efc4984e719d52d964332bd1c2
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:78e679efc4984e719d52d964332bd1c2
record_format dspace
spelling oai:doaj.org-article:78e679efc4984e719d52d964332bd1c22021-12-02T14:39:40ZZwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation10.1038/s41467-019-13238-72041-1723https://doaj.org/article/78e679efc4984e719d52d964332bd1c22019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13238-7https://doaj.org/toc/2041-1723Cellular overgrowth and fibrosis in the foreign body response can compromise the function of transplanted cells. Here, the authors report on the zwitterionically modified alginates for the encapsulation of cells to reduce cellular overgrowth and demonstrate application in mice, dogs and pigs.Qingsheng LiuAlan ChiuLong-Hai WangDuo AnMonica ZhongAlexandra M. SminkBart J. de HaanPaul de VosKevin KeaneAndreas VeggeEsther Y. ChenWei SongWendy F. LiuJames FlandersClaude RescanLars Groth GrunnetXi WangMinglin MaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Qingsheng Liu
Alan Chiu
Long-Hai Wang
Duo An
Monica Zhong
Alexandra M. Smink
Bart J. de Haan
Paul de Vos
Kevin Keane
Andreas Vegge
Esther Y. Chen
Wei Song
Wendy F. Liu
James Flanders
Claude Rescan
Lars Groth Grunnet
Xi Wang
Minglin Ma
Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation
description Cellular overgrowth and fibrosis in the foreign body response can compromise the function of transplanted cells. Here, the authors report on the zwitterionically modified alginates for the encapsulation of cells to reduce cellular overgrowth and demonstrate application in mice, dogs and pigs.
format article
author Qingsheng Liu
Alan Chiu
Long-Hai Wang
Duo An
Monica Zhong
Alexandra M. Smink
Bart J. de Haan
Paul de Vos
Kevin Keane
Andreas Vegge
Esther Y. Chen
Wei Song
Wendy F. Liu
James Flanders
Claude Rescan
Lars Groth Grunnet
Xi Wang
Minglin Ma
author_facet Qingsheng Liu
Alan Chiu
Long-Hai Wang
Duo An
Monica Zhong
Alexandra M. Smink
Bart J. de Haan
Paul de Vos
Kevin Keane
Andreas Vegge
Esther Y. Chen
Wei Song
Wendy F. Liu
James Flanders
Claude Rescan
Lars Groth Grunnet
Xi Wang
Minglin Ma
author_sort Qingsheng Liu
title Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation
title_short Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation
title_full Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation
title_fullStr Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation
title_full_unstemmed Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation
title_sort zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/78e679efc4984e719d52d964332bd1c2
work_keys_str_mv AT qingshengliu zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT alanchiu zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT longhaiwang zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT duoan zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT monicazhong zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT alexandramsmink zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT bartjdehaan zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT pauldevos zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT kevinkeane zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT andreasvegge zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT estherychen zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT weisong zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT wendyfliu zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT jamesflanders zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT clauderescan zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT larsgrothgrunnet zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT xiwang zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
AT minglinma zwitterionicallymodifiedalginatesmitigatecellularovergrowthforcellencapsulation
_version_ 1718390539010703360