Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation
Cellular overgrowth and fibrosis in the foreign body response can compromise the function of transplanted cells. Here, the authors report on the zwitterionically modified alginates for the encapsulation of cells to reduce cellular overgrowth and demonstrate application in mice, dogs and pigs.
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Nature Portfolio
2019
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oai:doaj.org-article:78e679efc4984e719d52d964332bd1c22021-12-02T14:39:40ZZwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation10.1038/s41467-019-13238-72041-1723https://doaj.org/article/78e679efc4984e719d52d964332bd1c22019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13238-7https://doaj.org/toc/2041-1723Cellular overgrowth and fibrosis in the foreign body response can compromise the function of transplanted cells. Here, the authors report on the zwitterionically modified alginates for the encapsulation of cells to reduce cellular overgrowth and demonstrate application in mice, dogs and pigs.Qingsheng LiuAlan ChiuLong-Hai WangDuo AnMonica ZhongAlexandra M. SminkBart J. de HaanPaul de VosKevin KeaneAndreas VeggeEsther Y. ChenWei SongWendy F. LiuJames FlandersClaude RescanLars Groth GrunnetXi WangMinglin MaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019) |
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Science Q |
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Science Q Qingsheng Liu Alan Chiu Long-Hai Wang Duo An Monica Zhong Alexandra M. Smink Bart J. de Haan Paul de Vos Kevin Keane Andreas Vegge Esther Y. Chen Wei Song Wendy F. Liu James Flanders Claude Rescan Lars Groth Grunnet Xi Wang Minglin Ma Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation |
description |
Cellular overgrowth and fibrosis in the foreign body response can compromise the function of transplanted cells. Here, the authors report on the zwitterionically modified alginates for the encapsulation of cells to reduce cellular overgrowth and demonstrate application in mice, dogs and pigs. |
format |
article |
author |
Qingsheng Liu Alan Chiu Long-Hai Wang Duo An Monica Zhong Alexandra M. Smink Bart J. de Haan Paul de Vos Kevin Keane Andreas Vegge Esther Y. Chen Wei Song Wendy F. Liu James Flanders Claude Rescan Lars Groth Grunnet Xi Wang Minglin Ma |
author_facet |
Qingsheng Liu Alan Chiu Long-Hai Wang Duo An Monica Zhong Alexandra M. Smink Bart J. de Haan Paul de Vos Kevin Keane Andreas Vegge Esther Y. Chen Wei Song Wendy F. Liu James Flanders Claude Rescan Lars Groth Grunnet Xi Wang Minglin Ma |
author_sort |
Qingsheng Liu |
title |
Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation |
title_short |
Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation |
title_full |
Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation |
title_fullStr |
Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation |
title_full_unstemmed |
Zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation |
title_sort |
zwitterionically modified alginates mitigate cellular overgrowth for cell encapsulation |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/78e679efc4984e719d52d964332bd1c2 |
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