Evaluation of Transfusion-Related Hemodynamic Parameters in Patients with Beta-Thalassemia Major by Ambulatory Blood Pressure Monitoring Method

Introduction: There are very few studies on the effects of regular blood transfusions on the hemodynamic organization of patients with Beta-Thalassemia Major (BTM). Ambulatory Blood Pressure Monitoring is method that evaluates fluctuations in day-night periods and life cycle changes. In this study,...

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Autores principales: Melis Aydın Mut, Emine Türkkan, Hüseyin Dağ, Hasan Dursun
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Lenguaje:EN
Publicado: Emergency Department of Hospital San Pedro (Logroño, Spain) 2021
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Acceso en línea:https://doi.org/10.5281/zenodo.4722801
https://doaj.org/article/78e7e7a7847b41ce9326ca6fd89a3530
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spelling oai:doaj.org-article:78e7e7a7847b41ce9326ca6fd89a35302021-12-02T17:45:29ZEvaluation of Transfusion-Related Hemodynamic Parameters in Patients with Beta-Thalassemia Major by Ambulatory Blood Pressure Monitoring Methodhttps://doi.org/10.5281/zenodo.47228012695-5075https://doaj.org/article/78e7e7a7847b41ce9326ca6fd89a35302021-04-01T00:00:00Zhttps://doi.org/10.5281/zenodo.4722801https://doaj.org/toc/2695-5075Introduction: There are very few studies on the effects of regular blood transfusions on the hemodynamic organization of patients with Beta-Thalassemia Major (BTM). Ambulatory Blood Pressure Monitoring is method that evaluates fluctuations in day-night periods and life cycle changes. In this study, we aimed to investigate the effects of blood transfusion on hemodynamic parameters by the Ambulatory Blood Pressure Monitoring method on the day of transfusion in patients with a diagnosis of Beta-Thalassemia Major. Material and Methods: This study was conducted in patients who were followed up with a diagnosis of BTM between June 2020 and July 2020. The study consisted of 30 patients. The blood pressure of the patients was measured by auscultation method on the morning of the day when they received routine red blood cell transfusion treatments, and the patients were fitted with an Ambulatory Blood Pressure Monitoring device. With Ambulatory Blood Pressure Monitoring, mean systolic blood pressure, diastolic blood pressure, heart rate, mean arterial pressure, values were calculated for each patient. Statistical analysis was performed by the IBM SPSS Statistics 21 package program. The significance limit for the p-value was accepted as <0.05. Results: There was a significant difference in mean systolic blood pressure and heart rate values between pre-transfusion, transfusion, and post-transfusion periods. In our study, the rate of white coat hypertension was 8.3%, and the rate of masked hypertension was 4.1%. It was observed that 67% of the patients were non-dippers, and the blood pressure burden of one patient was more than 25%. Conclusions: Measurement of hemodynamic parameters with Ambulatory Blood Pressure Monitoring is the gold standard in terms of detection and follow-up of non-dipper patients, indicating increased cardiovascular risk. In practice, Ambulatory Blood Pressure Monitoring should be used more in the follow-up of chronic patients.Melis Aydın MutEmine TürkkanHüseyin DağHasan DursunEmergency Department of Hospital San Pedro (Logroño, Spain)articlenon-dipperthalassemiatransfusionblood pressureMedicine (General)R5-920ENIberoamerican Journal of Medicine, Vol 3, Iss 3, Pp 187-195 (2021)
institution DOAJ
collection DOAJ
language EN
topic non-dipper
thalassemia
transfusion
blood pressure
Medicine (General)
R5-920
spellingShingle non-dipper
thalassemia
transfusion
blood pressure
Medicine (General)
R5-920
Melis Aydın Mut
Emine Türkkan
Hüseyin Dağ
Hasan Dursun
Evaluation of Transfusion-Related Hemodynamic Parameters in Patients with Beta-Thalassemia Major by Ambulatory Blood Pressure Monitoring Method
description Introduction: There are very few studies on the effects of regular blood transfusions on the hemodynamic organization of patients with Beta-Thalassemia Major (BTM). Ambulatory Blood Pressure Monitoring is method that evaluates fluctuations in day-night periods and life cycle changes. In this study, we aimed to investigate the effects of blood transfusion on hemodynamic parameters by the Ambulatory Blood Pressure Monitoring method on the day of transfusion in patients with a diagnosis of Beta-Thalassemia Major. Material and Methods: This study was conducted in patients who were followed up with a diagnosis of BTM between June 2020 and July 2020. The study consisted of 30 patients. The blood pressure of the patients was measured by auscultation method on the morning of the day when they received routine red blood cell transfusion treatments, and the patients were fitted with an Ambulatory Blood Pressure Monitoring device. With Ambulatory Blood Pressure Monitoring, mean systolic blood pressure, diastolic blood pressure, heart rate, mean arterial pressure, values were calculated for each patient. Statistical analysis was performed by the IBM SPSS Statistics 21 package program. The significance limit for the p-value was accepted as <0.05. Results: There was a significant difference in mean systolic blood pressure and heart rate values between pre-transfusion, transfusion, and post-transfusion periods. In our study, the rate of white coat hypertension was 8.3%, and the rate of masked hypertension was 4.1%. It was observed that 67% of the patients were non-dippers, and the blood pressure burden of one patient was more than 25%. Conclusions: Measurement of hemodynamic parameters with Ambulatory Blood Pressure Monitoring is the gold standard in terms of detection and follow-up of non-dipper patients, indicating increased cardiovascular risk. In practice, Ambulatory Blood Pressure Monitoring should be used more in the follow-up of chronic patients.
format article
author Melis Aydın Mut
Emine Türkkan
Hüseyin Dağ
Hasan Dursun
author_facet Melis Aydın Mut
Emine Türkkan
Hüseyin Dağ
Hasan Dursun
author_sort Melis Aydın Mut
title Evaluation of Transfusion-Related Hemodynamic Parameters in Patients with Beta-Thalassemia Major by Ambulatory Blood Pressure Monitoring Method
title_short Evaluation of Transfusion-Related Hemodynamic Parameters in Patients with Beta-Thalassemia Major by Ambulatory Blood Pressure Monitoring Method
title_full Evaluation of Transfusion-Related Hemodynamic Parameters in Patients with Beta-Thalassemia Major by Ambulatory Blood Pressure Monitoring Method
title_fullStr Evaluation of Transfusion-Related Hemodynamic Parameters in Patients with Beta-Thalassemia Major by Ambulatory Blood Pressure Monitoring Method
title_full_unstemmed Evaluation of Transfusion-Related Hemodynamic Parameters in Patients with Beta-Thalassemia Major by Ambulatory Blood Pressure Monitoring Method
title_sort evaluation of transfusion-related hemodynamic parameters in patients with beta-thalassemia major by ambulatory blood pressure monitoring method
publisher Emergency Department of Hospital San Pedro (Logroño, Spain)
publishDate 2021
url https://doi.org/10.5281/zenodo.4722801
https://doaj.org/article/78e7e7a7847b41ce9326ca6fd89a3530
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AT emineturkkan evaluationoftransfusionrelatedhemodynamicparametersinpatientswithbetathalassemiamajorbyambulatorybloodpressuremonitoringmethod
AT huseyindag evaluationoftransfusionrelatedhemodynamicparametersinpatientswithbetathalassemiamajorbyambulatorybloodpressuremonitoringmethod
AT hasandursun evaluationoftransfusionrelatedhemodynamicparametersinpatientswithbetathalassemiamajorbyambulatorybloodpressuremonitoringmethod
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