Structure-based dynamic analysis of the glycine cleavage system suggests key residues for control of a key reaction step
Han Zhang et al. report molecular dynamics simulations and mutational analysis of a key process of the E. coli glycine cleavage system, an important enzyme complex in C1 metabolism. They identify a key amino acid residue controlling the release of the swinging aminomethyl lipoate arm and increase th...
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Autores principales: | Han Zhang, Yuchen Li, Jinglei Nie, Jie Ren, An-Ping Zeng |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
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Materias: | |
Acceso en línea: | https://doaj.org/article/78e895b2a82e49aea72b3a9bd99928e3 |
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