Propofol infusions using a human target controlled infusion (TCI) pump in chimpanzees (Pan troglodytes)
Abstract Chimpanzees are genetically and physiologically similar to humans. Several pharmacokinetic models of propofol are available and target controlled infusion (TCI) of propofol is established in humans, but not in chimpanzees. The purpose of this study was to investigate if human pharmacokineti...
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Autores principales: | T. Miyabe-Nishiwaki, A. Kaneko, A. Yamanaka, N. Maeda, J. Suzuki, M. Tomonaga, T. Matsuzawa, K. Muta, R. Nishimura, I. Yajima, D. J. Eleveld, A. R. Absalom, K. Masui |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/78f7c10163e4481696e0b271349aa8bb |
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