Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group.

<h4>Objectives</h4>The risk factors that contribute to future functional disability after heart failure (HF) are poorly understood. The aim of this study was to determine potential risk factors to future functional disability after HF in the general older adult population in Japan.<h4...

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Autores principales:	Shuko Takahashi, Kozo Tanno, Yuki Yonekura, Masaki Ohsawa, Toru Kuribayashi, Yasuhiro Ishibashi, Shinichi Omama, Fumitaka Tanaka, Toshiyuki Onoda, Kiyomi Sakata, Makoto Koshiyama, Kazuyoshi Itai, Akira Okayama
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/790148f439f1493784bd89c6496597dd
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spelling	oai:doaj.org-article:790148f439f1493784bd89c6496597dd2021-12-02T20:10:58ZLow educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group.1932-620310.1371/journal.pone.0253017https://doaj.org/article/790148f439f1493784bd89c6496597dd2021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0253017https://doaj.org/toc/1932-6203<h4>Objectives</h4>The risk factors that contribute to future functional disability after heart failure (HF) are poorly understood. The aim of this study was to determine potential risk factors to future functional disability after HF in the general older adult population in Japan.<h4>Methods</h4>The subjects who were community-dwelling older adults aged 65 or older without a history of cardiovascular diseases and functional disability were followed in this prospective study for 11 years. Two case groups were determined from the 4,644 subjects: no long-term care insurance (LTCI) after HF (n = 52) and LTCI after HF (n = 44). We selected the controls by randomly matching each case of HF with three of the remaining 4,548 subjects who were event-free during the period: those with no LTCI and no HF with age +/-1 years and of the same sex, control for the no LTCI after HF group (n = 156), and control for the LTCI after HF group (n = 132). HF was diagnosed according to the Framingham diagnostic criteria. Individuals with a functional disability were those who had been newly certified by the LTCI during the observation period. Objective data including blood samples and several socioeconomic items in the baseline survey were assessed using a self-reported questionnaire.<h4>Results</h4>Significantly associated risk factors were lower educational levels (odds ratio (OR) [95% confidence interval (CI)]: 3.72 [1.63-8.48]) in the LTCI after HF group and hypertension (2.20 [1.10-4.43]) in no LTCI after HF group. Regular alcohol consumption and unmarried status were marginally significantly associated with LTCI after HF (OR [95% CI]; drinker = 2.69 [0.95-7.66]; P = 0.063; unmarried status = 2.54 [0.91-7.15]; P = 0.076).<h4>Conclusion</h4>Preventive measures must be taken to protect older adults with unfavorable social factors from disability after HF via a multidisciplinary approach.Shuko TakahashiKozo TannoYuki YonekuraMasaki OhsawaToru KuribayashiYasuhiro IshibashiShinichi OmamaFumitaka TanakaToshiyuki OnodaKiyomi SakataMakoto KoshiyamaKazuyoshi ItaiAkira OkayamaPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0253017 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Shuko Takahashi Kozo Tanno Yuki Yonekura Masaki Ohsawa Toru Kuribayashi Yasuhiro Ishibashi Shinichi Omama Fumitaka Tanaka Toshiyuki Onoda Kiyomi Sakata Makoto Koshiyama Kazuyoshi Itai Akira Okayama Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group.
description	<h4>Objectives</h4>The risk factors that contribute to future functional disability after heart failure (HF) are poorly understood. The aim of this study was to determine potential risk factors to future functional disability after HF in the general older adult population in Japan.<h4>Methods</h4>The subjects who were community-dwelling older adults aged 65 or older without a history of cardiovascular diseases and functional disability were followed in this prospective study for 11 years. Two case groups were determined from the 4,644 subjects: no long-term care insurance (LTCI) after HF (n = 52) and LTCI after HF (n = 44). We selected the controls by randomly matching each case of HF with three of the remaining 4,548 subjects who were event-free during the period: those with no LTCI and no HF with age +/-1 years and of the same sex, control for the no LTCI after HF group (n = 156), and control for the LTCI after HF group (n = 132). HF was diagnosed according to the Framingham diagnostic criteria. Individuals with a functional disability were those who had been newly certified by the LTCI during the observation period. Objective data including blood samples and several socioeconomic items in the baseline survey were assessed using a self-reported questionnaire.<h4>Results</h4>Significantly associated risk factors were lower educational levels (odds ratio (OR) [95% confidence interval (CI)]: 3.72 [1.63-8.48]) in the LTCI after HF group and hypertension (2.20 [1.10-4.43]) in no LTCI after HF group. Regular alcohol consumption and unmarried status were marginally significantly associated with LTCI after HF (OR [95% CI]; drinker = 2.69 [0.95-7.66]; P = 0.063; unmarried status = 2.54 [0.91-7.15]; P = 0.076).<h4>Conclusion</h4>Preventive measures must be taken to protect older adults with unfavorable social factors from disability after HF via a multidisciplinary approach.
format	article
author	Shuko Takahashi Kozo Tanno Yuki Yonekura Masaki Ohsawa Toru Kuribayashi Yasuhiro Ishibashi Shinichi Omama Fumitaka Tanaka Toshiyuki Onoda Kiyomi Sakata Makoto Koshiyama Kazuyoshi Itai Akira Okayama
author_facet	Shuko Takahashi Kozo Tanno Yuki Yonekura Masaki Ohsawa Toru Kuribayashi Yasuhiro Ishibashi Shinichi Omama Fumitaka Tanaka Toshiyuki Onoda Kiyomi Sakata Makoto Koshiyama Kazuyoshi Itai Akira Okayama
author_sort	Shuko Takahashi
title	Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group.
title_short	Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group.
title_full	Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group.
title_fullStr	Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group.
title_full_unstemmed	Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group.
title_sort	low educational level increases functional disability risk subsequent to heart failure in japan: on behalf of the iwate kenco study group.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/790148f439f1493784bd89c6496597dd
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Low educational level increases functional disability risk subsequent to heart failure in Japan: On behalf of the Iwate KENCO study group.

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