Cerebral Autoregulation in Non-Brain Injured Patients: A Systematic Review
Introduction: Cerebral autoregulation (CA) plays a fundamental role in the maintenance of adequate cerebral blood flow (CBF). CA monitoring, through direct and indirect techniques, may guide an appropriate therapeutic approach aimed at improving CBF and reducing neurological complications; so far, t...
Guardado en:
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Frontiers Media S.A.
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/790b3a67c1b742b6830bbbbea698cfcc |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:790b3a67c1b742b6830bbbbea698cfcc |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:790b3a67c1b742b6830bbbbea698cfcc2021-11-16T07:37:14ZCerebral Autoregulation in Non-Brain Injured Patients: A Systematic Review1664-229510.3389/fneur.2021.732176https://doaj.org/article/790b3a67c1b742b6830bbbbea698cfcc2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fneur.2021.732176/fullhttps://doaj.org/toc/1664-2295Introduction: Cerebral autoregulation (CA) plays a fundamental role in the maintenance of adequate cerebral blood flow (CBF). CA monitoring, through direct and indirect techniques, may guide an appropriate therapeutic approach aimed at improving CBF and reducing neurological complications; so far, the role of CA has been investigated mainly in brain-injured patients. The aim of this study is to investigate the role of CA in non-brain injured patients.Methods: A systematic consultation of literature was carried out. Search terms included: “CA and sepsis,” “CA and surgery,” and “CA and non-brain injury.”Results: Our research individualized 294 studies and after screening, 22 studies were analyzed in this study. Studies were divided in three groups: CA in sepsis and septic shock, CA during surgery, and CA in the pediatric population. Studies in sepsis and intraoperative setting highlighted a relationship between the incidence of sepsis-associated delirium and impaired CA. The most investigated setting in the pediatric population is cardiac surgery, but the role and measurement of CA need to be further elucidated.Conclusion: In non-brain injured patients, impaired CA may result in cognitive dysfunction, neurological damage, worst outcome, and increased mortality. Monitoring CA might be a useful tool for the bedside optimization and individualization of the clinical management in this group of patients.Yaroslava LonghitanoFrancesca IannuzziGiulia BonattiChristian ZanzaAntonio MessinaAntonio MessinaDaniel GodoyWojciech DabrowskiLi XiuyunMarek CzosnykaPaolo PelosiPaolo PelosiRafael BadenesChiara RobbaChiara RobbaFrontiers Media S.A.articlecerebral autoregulationnon-brain injuryneurologic outcomesepsisperioperative carepediatric surgeryNeurology. Diseases of the nervous systemRC346-429ENFrontiers in Neurology, Vol 12 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
cerebral autoregulation non-brain injury neurologic outcome sepsis perioperative care pediatric surgery Neurology. Diseases of the nervous system RC346-429 |
| spellingShingle |
cerebral autoregulation non-brain injury neurologic outcome sepsis perioperative care pediatric surgery Neurology. Diseases of the nervous system RC346-429 Yaroslava Longhitano Francesca Iannuzzi Giulia Bonatti Christian Zanza Antonio Messina Antonio Messina Daniel Godoy Wojciech Dabrowski Li Xiuyun Marek Czosnyka Paolo Pelosi Paolo Pelosi Rafael Badenes Chiara Robba Chiara Robba Cerebral Autoregulation in Non-Brain Injured Patients: A Systematic Review |
| description |
Introduction: Cerebral autoregulation (CA) plays a fundamental role in the maintenance of adequate cerebral blood flow (CBF). CA monitoring, through direct and indirect techniques, may guide an appropriate therapeutic approach aimed at improving CBF and reducing neurological complications; so far, the role of CA has been investigated mainly in brain-injured patients. The aim of this study is to investigate the role of CA in non-brain injured patients.Methods: A systematic consultation of literature was carried out. Search terms included: “CA and sepsis,” “CA and surgery,” and “CA and non-brain injury.”Results: Our research individualized 294 studies and after screening, 22 studies were analyzed in this study. Studies were divided in three groups: CA in sepsis and septic shock, CA during surgery, and CA in the pediatric population. Studies in sepsis and intraoperative setting highlighted a relationship between the incidence of sepsis-associated delirium and impaired CA. The most investigated setting in the pediatric population is cardiac surgery, but the role and measurement of CA need to be further elucidated.Conclusion: In non-brain injured patients, impaired CA may result in cognitive dysfunction, neurological damage, worst outcome, and increased mortality. Monitoring CA might be a useful tool for the bedside optimization and individualization of the clinical management in this group of patients. |
| format |
article |
| author |
Yaroslava Longhitano Francesca Iannuzzi Giulia Bonatti Christian Zanza Antonio Messina Antonio Messina Daniel Godoy Wojciech Dabrowski Li Xiuyun Marek Czosnyka Paolo Pelosi Paolo Pelosi Rafael Badenes Chiara Robba Chiara Robba |
| author_facet |
Yaroslava Longhitano Francesca Iannuzzi Giulia Bonatti Christian Zanza Antonio Messina Antonio Messina Daniel Godoy Wojciech Dabrowski Li Xiuyun Marek Czosnyka Paolo Pelosi Paolo Pelosi Rafael Badenes Chiara Robba Chiara Robba |
| author_sort |
Yaroslava Longhitano |
| title |
Cerebral Autoregulation in Non-Brain Injured Patients: A Systematic Review |
| title_short |
Cerebral Autoregulation in Non-Brain Injured Patients: A Systematic Review |
| title_full |
Cerebral Autoregulation in Non-Brain Injured Patients: A Systematic Review |
| title_fullStr |
Cerebral Autoregulation in Non-Brain Injured Patients: A Systematic Review |
| title_full_unstemmed |
Cerebral Autoregulation in Non-Brain Injured Patients: A Systematic Review |
| title_sort |
cerebral autoregulation in non-brain injured patients: a systematic review |
| publisher |
Frontiers Media S.A. |
| publishDate |
2021 |
| url |
https://doaj.org/article/790b3a67c1b742b6830bbbbea698cfcc |
| work_keys_str_mv |
AT yaroslavalonghitano cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT francescaiannuzzi cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT giuliabonatti cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT christianzanza cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT antoniomessina cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT antoniomessina cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT danielgodoy cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT wojciechdabrowski cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT lixiuyun cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT marekczosnyka cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT paolopelosi cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT paolopelosi cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT rafaelbadenes cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT chiararobba cerebralautoregulationinnonbraininjuredpatientsasystematicreview AT chiararobba cerebralautoregulationinnonbraininjuredpatientsasystematicreview |
| _version_ |
1718426611750010880 |