High-Resolution Morphological Approach to Analyse Elastic Laminae Injuries of the Ascending Aorta in a Murine Model of Marfan Syndrome

Abstract In Marfan syndrome, the tunica media is disrupted, which leads to the formation of ascending aortic aneurysms. Marfan aortic samples are histologically characterized by the fragmentation of elastic laminae. However, conventional histological techniques using transverse sections provide limi...

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Bibliographic Details
Main Authors: Júlia López-Guimet, Jordi Andilla, Pablo Loza-Alvarez, Gustavo Egea
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/7910d0dc307d4d15880b3866975d6f2e
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