Accelerated single cell seeding in relapsed multiple myeloma

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Accelerated single cell seeding in relapsed multiple myeloma

In multiple myeloma, disease progresses via seeding to different anatomic sites and clonal expansion. Here, utilising autopsy material, the authors show that systemic seeding accelerates at relapse following treatment.

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Detalles Bibliográficos
Autores principales:	Heather J. Landau, Venkata Yellapantula, Benjamin T. Diamond, Even H. Rustad, Kylee H. Maclachlan, Gunes Gundem, Juan Medina-Martinez, Juan Arango Ossa, Max F. Levine, Yangyu Zhou, Rajya Kappagantula, Priscilla Baez, Marc Attiyeh, Alvin Makohon-Moore, Lance Zhang, Eileen M. Boyle, Cody Ashby, Patrick Blaney, Minal Patel, Yanming Zhang, Ahmet Dogan, David J. Chung, Sergio Giralt, Oscar B. Lahoud, Jonathan U. Peled, Michael Scordo, Gunjan Shah, Hani Hassoun, Neha S. Korde, Alexander M. Lesokhin, Sydney Lu, Sham Mailankody, Urvi Shah, Eric Smith, Malin L. Hultcrantz, Gary A. Ulaner, Frits van Rhee, Gareth J. Morgan, Ola Landgren, Elli Papaemmanuil, Christine Iacobuzio-Donahue, Francesco Maura
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/79126e7bfea74892ac4947e64f7abb17
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Descripción
Sumario:	In multiple myeloma, disease progresses via seeding to different anatomic sites and clonal expansion. Here, utilising autopsy material, the authors show that systemic seeding accelerates at relapse following treatment.