Accelerated single cell seeding in relapsed multiple myeloma
In multiple myeloma, disease progresses via seeding to different anatomic sites and clonal expansion. Here, utilising autopsy material, the authors show that systemic seeding accelerates at relapse following treatment.
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Nature Portfolio
2020
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oai:doaj.org-article:79126e7bfea74892ac4947e64f7abb172021-12-02T18:37:05ZAccelerated single cell seeding in relapsed multiple myeloma10.1038/s41467-020-17459-z2041-1723https://doaj.org/article/79126e7bfea74892ac4947e64f7abb172020-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-17459-zhttps://doaj.org/toc/2041-1723In multiple myeloma, disease progresses via seeding to different anatomic sites and clonal expansion. Here, utilising autopsy material, the authors show that systemic seeding accelerates at relapse following treatment.Heather J. LandauVenkata YellapantulaBenjamin T. DiamondEven H. RustadKylee H. MaclachlanGunes GundemJuan Medina-MartinezJuan Arango OssaMax F. LevineYangyu ZhouRajya KappagantulaPriscilla BaezMarc AttiyehAlvin Makohon-MooreLance ZhangEileen M. BoyleCody AshbyPatrick BlaneyMinal PatelYanming ZhangAhmet DoganDavid J. ChungSergio GiraltOscar B. LahoudJonathan U. PeledMichael ScordoGunjan ShahHani HassounNeha S. KordeAlexander M. LesokhinSydney LuSham MailankodyUrvi ShahEric SmithMalin L. HultcrantzGary A. UlanerFrits van RheeGareth J. MorganOla LandgrenElli PapaemmanuilChristine Iacobuzio-DonahueFrancesco MauraNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020) |
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DOAJ |
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DOAJ |
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EN |
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Science Q |
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Science Q Heather J. Landau Venkata Yellapantula Benjamin T. Diamond Even H. Rustad Kylee H. Maclachlan Gunes Gundem Juan Medina-Martinez Juan Arango Ossa Max F. Levine Yangyu Zhou Rajya Kappagantula Priscilla Baez Marc Attiyeh Alvin Makohon-Moore Lance Zhang Eileen M. Boyle Cody Ashby Patrick Blaney Minal Patel Yanming Zhang Ahmet Dogan David J. Chung Sergio Giralt Oscar B. Lahoud Jonathan U. Peled Michael Scordo Gunjan Shah Hani Hassoun Neha S. Korde Alexander M. Lesokhin Sydney Lu Sham Mailankody Urvi Shah Eric Smith Malin L. Hultcrantz Gary A. Ulaner Frits van Rhee Gareth J. Morgan Ola Landgren Elli Papaemmanuil Christine Iacobuzio-Donahue Francesco Maura Accelerated single cell seeding in relapsed multiple myeloma |
| description |
In multiple myeloma, disease progresses via seeding to different anatomic sites and clonal expansion. Here, utilising autopsy material, the authors show that systemic seeding accelerates at relapse following treatment. |
| format |
article |
| author |
Heather J. Landau Venkata Yellapantula Benjamin T. Diamond Even H. Rustad Kylee H. Maclachlan Gunes Gundem Juan Medina-Martinez Juan Arango Ossa Max F. Levine Yangyu Zhou Rajya Kappagantula Priscilla Baez Marc Attiyeh Alvin Makohon-Moore Lance Zhang Eileen M. Boyle Cody Ashby Patrick Blaney Minal Patel Yanming Zhang Ahmet Dogan David J. Chung Sergio Giralt Oscar B. Lahoud Jonathan U. Peled Michael Scordo Gunjan Shah Hani Hassoun Neha S. Korde Alexander M. Lesokhin Sydney Lu Sham Mailankody Urvi Shah Eric Smith Malin L. Hultcrantz Gary A. Ulaner Frits van Rhee Gareth J. Morgan Ola Landgren Elli Papaemmanuil Christine Iacobuzio-Donahue Francesco Maura |
| author_facet |
Heather J. Landau Venkata Yellapantula Benjamin T. Diamond Even H. Rustad Kylee H. Maclachlan Gunes Gundem Juan Medina-Martinez Juan Arango Ossa Max F. Levine Yangyu Zhou Rajya Kappagantula Priscilla Baez Marc Attiyeh Alvin Makohon-Moore Lance Zhang Eileen M. Boyle Cody Ashby Patrick Blaney Minal Patel Yanming Zhang Ahmet Dogan David J. Chung Sergio Giralt Oscar B. Lahoud Jonathan U. Peled Michael Scordo Gunjan Shah Hani Hassoun Neha S. Korde Alexander M. Lesokhin Sydney Lu Sham Mailankody Urvi Shah Eric Smith Malin L. Hultcrantz Gary A. Ulaner Frits van Rhee Gareth J. Morgan Ola Landgren Elli Papaemmanuil Christine Iacobuzio-Donahue Francesco Maura |
| author_sort |
Heather J. Landau |
| title |
Accelerated single cell seeding in relapsed multiple myeloma |
| title_short |
Accelerated single cell seeding in relapsed multiple myeloma |
| title_full |
Accelerated single cell seeding in relapsed multiple myeloma |
| title_fullStr |
Accelerated single cell seeding in relapsed multiple myeloma |
| title_full_unstemmed |
Accelerated single cell seeding in relapsed multiple myeloma |
| title_sort |
accelerated single cell seeding in relapsed multiple myeloma |
| publisher |
Nature Portfolio |
| publishDate |
2020 |
| url |
https://doaj.org/article/79126e7bfea74892ac4947e64f7abb17 |
| work_keys_str_mv |
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1718377869609009152 |