Genomic patterns of progression in smoldering multiple myeloma

Smoldering MM (SMM) is a premalignant stage of multiple myeloma (MM). Here the authors perform whole genome sequencing of unique paired samples of SMM progressing to MM, and show that the genomic landscape at the SMM stage is very similar to MM, but trajectories of evolution can vary from patient to...

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Autores principales:	Niccolò Bolli, Francesco Maura, Stephane Minvielle, Dominik Gloznik, Raphael Szalat, Anthony Fullam, Inigo Martincorena, Kevin J. Dawson, Mehmet Kemal Samur, Jorge Zamora, Patrick Tarpey, Helen Davies, Mariateresa Fulciniti, Masood A. Shammas, Yu Tzu Tai, Florence Magrangeas, Philippe Moreau, Paolo Corradini, Kenneth Anderson, Ludmil Alexandrov, David C. Wedge, Herve Avet-Loiseau, Peter Campbell, Nikhil Munshi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7915841302254896b2f39285aed1718f
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spelling	oai:doaj.org-article:7915841302254896b2f39285aed1718f2021-12-02T17:32:34ZGenomic patterns of progression in smoldering multiple myeloma10.1038/s41467-018-05058-y2041-1723https://doaj.org/article/7915841302254896b2f39285aed1718f2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05058-yhttps://doaj.org/toc/2041-1723Smoldering MM (SMM) is a premalignant stage of multiple myeloma (MM). Here the authors perform whole genome sequencing of unique paired samples of SMM progressing to MM, and show that the genomic landscape at the SMM stage is very similar to MM, but trajectories of evolution can vary from patient to patient.Niccolò BolliFrancesco MauraStephane MinvielleDominik GloznikRaphael SzalatAnthony FullamInigo MartincorenaKevin J. DawsonMehmet Kemal SamurJorge ZamoraPatrick TarpeyHelen DaviesMariateresa FulcinitiMasood A. ShammasYu Tzu TaiFlorence MagrangeasPhilippe MoreauPaolo CorradiniKenneth AndersonLudmil AlexandrovDavid C. WedgeHerve Avet-LoiseauPeter CampbellNikhil MunshiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Niccolò Bolli Francesco Maura Stephane Minvielle Dominik Gloznik Raphael Szalat Anthony Fullam Inigo Martincorena Kevin J. Dawson Mehmet Kemal Samur Jorge Zamora Patrick Tarpey Helen Davies Mariateresa Fulciniti Masood A. Shammas Yu Tzu Tai Florence Magrangeas Philippe Moreau Paolo Corradini Kenneth Anderson Ludmil Alexandrov David C. Wedge Herve Avet-Loiseau Peter Campbell Nikhil Munshi Genomic patterns of progression in smoldering multiple myeloma
description	Smoldering MM (SMM) is a premalignant stage of multiple myeloma (MM). Here the authors perform whole genome sequencing of unique paired samples of SMM progressing to MM, and show that the genomic landscape at the SMM stage is very similar to MM, but trajectories of evolution can vary from patient to patient.
format	article
author	Niccolò Bolli Francesco Maura Stephane Minvielle Dominik Gloznik Raphael Szalat Anthony Fullam Inigo Martincorena Kevin J. Dawson Mehmet Kemal Samur Jorge Zamora Patrick Tarpey Helen Davies Mariateresa Fulciniti Masood A. Shammas Yu Tzu Tai Florence Magrangeas Philippe Moreau Paolo Corradini Kenneth Anderson Ludmil Alexandrov David C. Wedge Herve Avet-Loiseau Peter Campbell Nikhil Munshi
author_facet	Niccolò Bolli Francesco Maura Stephane Minvielle Dominik Gloznik Raphael Szalat Anthony Fullam Inigo Martincorena Kevin J. Dawson Mehmet Kemal Samur Jorge Zamora Patrick Tarpey Helen Davies Mariateresa Fulciniti Masood A. Shammas Yu Tzu Tai Florence Magrangeas Philippe Moreau Paolo Corradini Kenneth Anderson Ludmil Alexandrov David C. Wedge Herve Avet-Loiseau Peter Campbell Nikhil Munshi
author_sort	Niccolò Bolli
title	Genomic patterns of progression in smoldering multiple myeloma
title_short	Genomic patterns of progression in smoldering multiple myeloma
title_full	Genomic patterns of progression in smoldering multiple myeloma
title_fullStr	Genomic patterns of progression in smoldering multiple myeloma
title_full_unstemmed	Genomic patterns of progression in smoldering multiple myeloma
title_sort	genomic patterns of progression in smoldering multiple myeloma
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/7915841302254896b2f39285aed1718f
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Genomic patterns of progression in smoldering multiple myeloma

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